76697-58-0 Usage
Description
1-AMINO-2-(PROPYLSULPHONYL)BENZENE, also known as N-propyl-p-toluenesulfonamide, is a chemical compound with the molecular formula C9H13NO2S. It features a benzene ring with a propylsulfonyl group attached to the amino group at the para position. 1-AMINO-2-(PROPYLSULPHONYL)BENZENE is recognized for its versatile reactivity and stable structure, making it a valuable building block in the synthesis of pharmaceuticals, agrochemicals, dyes, pigments, and other specialty chemicals.
Uses
Used in Pharmaceutical and Agrochemical Synthesis:
1-AMINO-2-(PROPYLSULPHONYL)BENZENE is used as a key building block for the development of new pharmaceuticals and agrochemicals. Its unique structure and reactivity allow for the creation of a wide range of active compounds with potential therapeutic and pesticidal properties.
Used in Dye and Pigment Production:
1-AMINO-2-(PROPYLSULPHONYL)BENZENE serves as an intermediate in the production of various dyes and pigments, contributing to the coloration and stability of these products in different applications.
Used in Specialty Chemicals Manufacturing:
1-AMINO-2-(PROPYLSULPHONYL)BENZENE is utilized in the synthesis of specialty chemicals, which are often used in specific industries for their unique properties, such as high performance or specific reactivity.
Used in Plasticizer and Lubricant Production:
1-AMINO-2-(PROPYLSULPHONYL)BENZENE also finds applications in the production of plasticizers and lubricants, where it enhances the flexibility, workability, and performance of these materials in various industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 76697-58-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,6,9 and 7 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 76697-58:
(7*7)+(6*6)+(5*6)+(4*9)+(3*7)+(2*5)+(1*8)=190
190 % 10 = 0
So 76697-58-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H13NO2S/c1-2-7-13(11,12)9-6-4-3-5-8(9)10/h3-6H,2,7,10H2,1H3
76697-58-0Relevant articles and documents
Visible-Light-Promoted Remote C-H Functionalization of o-Diazoniaphenyl Alkyl Sulfones
Du, Shaofu,Kimball, Elizabeth Ann,Ragains, Justin R.
supporting information, p. 5553 - 5556 (2017/10/25)
Visible-light irradiation of ortho-diazoniaphenyl alkyl sulfones in the presence of Ru(bpy)32+ results in remote Csp3-H functionalization. Key mechanistic steps in these processes involve intramolecular hydrogen atom transfer from Csp3-H bonds to aryl radicals to generate alkyl/benzyl radicals. Subsequent polar crossover occurs by single-electron oxidation of the alkyl/benzyl radicals to carbenium ions that then intercept nucleophiles. We have developed remote hydroxylations, etherifications, an amidation, and C-C bond formation processes using this strategy.
2-(Anilinomethyl)imidazolines as α1 adrenergic receptor agonists: The discovery of α10 subtype selective 2′-alkylsulfonyl-substituted analogues
Hodson, Stephen J.,Bishop, Michael J.,Speake, Jason D.,Navas III, Frank,Garrison, Deanna T.,Bigham, Eric C.,Saussy Jr., David L.,Liacos, James A.,Irving, Paul E.,Jeffrey Gobel,Sherman, Bryan W.
, p. 2229 - 2239 (2007/10/03)
A series of 2′-alkylthio-2-(anilinomethyl)imidazolines were prepared to examine the effect of the alkyl group size, sulfur oxidation state, and phenyl ring substitution on ligand binding and agonism of α-adrenergic receptor subtypes α1a, α1b, α1d, α2a, and α2c. Binding at all receptor subtypes decreased for compounds in the sulfone oxidation state as compared to their sulfide analogues. While sulfides were generally potent, nonselective agonists, sulfones exhibited α1a subtype selectivity in a cell-based functional assay. Sulfone (32) was 250-7000-fold selective for α1a vs all other subtypes.
