767-71-5

Basic information

• Product Name: N,2,6-trimethylaniline
• Synonyms: N,2,6-trimethylaniline;(2,6-dimethylphenyl)-methyl-amine;benzenamine, N,2,6-trimethyl-;Benzenamine,N,2,6-trimethyl-;InChI=1/C9H13N/c1-7-5-4-6-8(2)9(7)10-3/h4-6,10H,1-3H;N,2,6-Trimethylbenzenamine
• CAS NO: 767-71-5
• Molecular Formula: C₉H₁₃N
• Molecular Weight: 135.21
• Mol File: 767-71-5.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 223.2°C at 760 mmHg
• Flash Point: 88.4°C
• Appearance: /
• Density: 0.955g/cm³
• Vapor Pressure: 0.0974mmHg at 25°C
• Refractive Index: 1.556
• PKA: 4.60±0.10(Predicted)
• CAS DataBase Reference: N,2,6-trimethylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N,2,6-trimethylaniline(767-71-5)
• EPA Substance Registry System: N,2,6-trimethylaniline(767-71-5)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 767-71-5(Hazardous Substances Data)

Usage

General Description

N,2,6-trimethylaniline is a chemical compound that belongs to the class of aromatic amines. It is a colorless to pale yellow liquid with a strong odor. N,2,6-trimethylaniline is mainly used as an intermediate in the production of dyes and pigments, as well as in the synthesis of various pharmaceuticals and agrochemicals. It is also used as a chemical intermediate in the manufacture of rubber chemicals and antioxidants. N,2,6-trimethylaniline is considered to be harmful if swallowed, inhaled or absorbed through the skin, and it is classified as a hazardous substance. Therefore, proper safety measures should be taken when handling this chemical.

InChI:InChI=1/C9H13N/c1-7-5-4-6-8(2)9(7)10-3/h4-6,10H,1-3H3

Upstream product

• 98-04-4 phenyltrimethylammonium iodide 
• 77-78-1 dimethyl sulfate 
• 87-62-7 2,6-dimethylaniline 
• 74-88-4 methyl iodide 
• 607-92-1 2,6-dimethylformanilide 
• 156267-20-8 benzyl N-(2,6-dimethylphenyl)-N-methylcarbamate 
• 35203-02-2 2,6-dimethyl-N-methylene benzamine 
• 616-38-6 carbonic acid dimethyl ester 
• 769-06-2 N,N,2,6-tetramethylaniline 
• 156267-16-2 benzyl N-(2,6-dimethylphenyl)carbamate 
• 53782-79-9 (E)-4-(pent-3-en-2-yl)morpholine 
• 107-02-8 acrolein 
• 27237-52-1 N-methyl-N-2,6-dimethylphenylcarbamoylchloride 
• 333-27-7 methyl trifluoromethanesulfonate 

Downstream Products

• 111438-57-4 N,N'-bis-(2,6-dimethyl-phenyl)-N,N'-dimethyl-butanediyldiamine 
• 769-06-2 N,N,2,6-tetramethylaniline 
• 132984-55-5 (+/-)-trans-2-(2,6,N-Trimethyl-anilino)-cyclohexanol 
• 18835-47-7 N-(2,6-dimethylphenyl)-N-methylacetamide 
• 123103-29-7 succinic acid bis-(2,6,N-trimethyl-anilide) 
• 101581-78-6 2,6,N-trimethyl-N-phenethyl-aniline 
• 100319-52-6 N-(3-bromo-propyl)-2,6,N-trimethyl-aniline 
• 100452-08-2 N-(4-chloro-butyl)-2,6,N-trimethyl-aniline 
• 113651-87-9 N,N'-bis-(2,6-dimethyl-phenyl)-N,N'-dimethyl-but-2-ynediyldiamine 
• 35517-66-9 N-(2,6-Dimethylphenyl)-N-methylformamide 
• 830-52-4 [N-methyl-N-(2,6-dimethylphenyl)aminocarbonylmethyl]chloride 
• 83843-13-4 1-[N-methyl-N-(2,6-dimethylphenyl)-amino]-2-propanol 
• 67358-21-8 1,7-dimethylindolin-2-one 
• 156136-68-4 1,7-Dimethyl-1,3-dihydro-indole-2-thione 

Relevant articles and documents

Low-Temperature Intramolecular [4+2] Cycloaddition of Allenes with Arenes for the Synthesis of Diene Ligands

The intramolecular [4+2] cycloaddition between arenes and allenes first reported by Himbert gives rapid access to rigid polycyclic scaffolds. Herein, we report a one-pot oxyalkynylation/cycloaddition reaction proceeding under mild conditions (23–90 °C) an

Selective monomethylation of primary amines with simple electrophiles

Direct monomethylation of primary amines with methyl triflate was achieved with high selectivity (up to 96%). The key point of this single methyl transfer stems from the use of HFIP as the solvent that interferes with amines and avoids overmethylation.

INDAZOLEPROPIONIC ACID AMIDE COMPOUND

Disclosed is a compound which is useful in preventing and treating cardiac arrhythmia such as atrial fibrillation. A compound represented by formula (1) or a pharmaceutically acceptable salt of the same. In formula (1), ring X represents benzene or pyridine; R1 represents an optionally substituted alkyl group; R2 represents an optionally substituted aryl group, an optionally substituted heterocyclic group, an optionally substituted arylalkyl group or an optionally substituted heterocyclic group-substituted alkyl group; R3, R4, R5, R6, R7, R8 and R9 represent each hydrogen or an alkyl group, provided that R3 and R5 may be bonded to each other to form, together with the carbon atom adjacent thereto, a cycloalkyl group; and m represents 0 or 1.