767289-08-7

Basic information

• Product Name: N-(2-bromo-5-methoxybenzyl),N-methylamine
• Synonyms: N-(2-bromo-5-methoxybenzyl),N-methylamine
• CAS NO: 767289-08-7
• Molecular Weight: 230.104
• Mol File: 767289-08-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(2-bromo-5-methoxybenzyl),N-methylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-bromo-5-methoxybenzyl),N-methylamine(767289-08-7)
• EPA Substance Registry System: N-(2-bromo-5-methoxybenzyl),N-methylamine(767289-08-7)

Safety Data

• Hazardous Substances Data: 767289-08-7(Hazardous Substances Data)

Upstream product

• 7507-86-0 2-bromo-5-methoxy-benzaldehyde 
• 74-89-5 methylamine 
• 19614-12-1 2-bromo-5-methoxybenzyl bromide 

Downstream Products

• 205676-67-1 3-[N-(tert-butoxycarbonyl)-N-methylamino]methyl-4-bromoanisole 
• 1520080-21-0 isopropyl 2-bromo-5-methoxybenzyl(methyl)carbamate 
• 205676-68-2 Methyl (+/-)-3-carbomethoxy-4-[2-[N-(tert-butoxycarbonyl)-N-methylamino]methyl-4-methoxyphenyl]butanoate 
• 205676-69-3 methyl (+/-)-3-carbomethoxy-4-[2-(methylamino)methyl-4-methoxyphenyl]butanoate 
• 1263788-28-8 C₁₈H₁₇BrN₂O₂ 
• 880105-01-1 4-methyl-benzenesulfinic acid (2-bromo-5-methoxy-benzyl)-methyl-amide 
• 767289-10-1 4-[N-methyl-N-(2'-bromo-5'-methoxybenzyl)]amino-6-tertiarybutylbenzopyran-7-one 
• 1148107-95-2 6-((2-bromo-5-methoxybenzyl)(methyl)amino)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione 
• 1144029-15-1 C₁₂H₁₄BrNO₂ 

Relevant articles and documents

Smooth isoindolinone formation from isopropyl carbamates via bischler-napieralski-type cyclization

Isopropyl carbamates derived from benzylamines provide isoindolinones by treatment with phosphorus pentoxide at room temperature. Utility of this Bischler-Napieralski-type cyclization and a new mechanism involving a carbamoyl cation for rationalization of this smooth conversion are discussed.

Treatment Method

The present invention is directed to methods of treating an ocular neovascular disorder in a mammal by administration of pyrimidine derivatives, benzodiazepinyl derivatives and pharmaceutical compositions containing the same. The invention encompasses methods of treating an ocular neovascular disorder by administration of 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide, (S)-3-oxo-8-[3-(pyridin-2-ylamino)-1-propyloxy]-2-(2,2,2-trifluoroethyl)-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetic acid or salts or solvates thereof. Combination therapies for the treatment of ocular neovascular disorders are also encompassed.