76746-94-6

Basic information

• Product Name: 7-methoxyisoquinoline-1,3(2H,4H)-dione
• Synonyms: 7-methoxyisoquinoline-1,3(2H,4H)-dione;7-Methoxy-1,3(2H,4H)-isoquinolinedione;7-Methoxy-1,2,3,4-tetrahydroisoquinoline-1,3-dione
• CAS NO: 76746-94-6
• Molecular Formula: C10H9NO3
• Molecular Weight: 191.185
• Mol File: 76746-94-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 425.8 °C at 760 mmHg
• Flash Point: 211.3 °C
• Appearance: /
• Density: 1.280
• Vapor Pressure: 1.86E-07mmHg at 25°C
• Refractive Index: 1.566
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 7-methoxyisoquinoline-1,3(2H,4H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 7-methoxyisoquinoline-1,3(2H,4H)-dione(76746-94-6)
• EPA Substance Registry System: 7-methoxyisoquinoline-1,3(2H,4H)-dione(76746-94-6)

Safety Data

• Hazardous Substances Data: 76746-94-6(Hazardous Substances Data)

Usage

General Description

7-methoxyisoquinoline-1,3(2H,4H)-dione is a chemical compound that belongs to the class of isoquinoline derivatives. It is a yellow crystalline solid that is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. 7-methoxyisoquinoline-1,3(2H,4H)-dione has been studied for its potential biological activities, including its anticancer, anti-inflammatory, and antimicrobial properties. It is also used as a building block in the synthesis of various pharmaceuticals and agrochemicals. Additionally, 7-methoxyisoquinoline-1,3(2H,4H)-dione has been investigated for its potential as a fluorescent probe for sensing metal ions and as a photosensitizer for photodynamic therapy. Overall, this compound has a wide range of potential applications in various fields due to its diverse chemical and biological properties.

InChI:InChI=1/C10H9NO3/c1-14-7-3-2-6-4-9(12)11-10(13)8(6)5-7/h2-3,5H,4H2,1H3,(H,11,12,13)

Upstream product

• 25113-06-8 7-Methoxy-4-acetylisochroman-1,3-dione 
• 63485-72-3 4-carboethoxy-7-methoxy-3-methylisocoumarin 
• 25113-11-5 4-carbomethoxy-7-methoxy-3-methylisocoumarin 
• 4702-29-8 7-methoxy-1H-isochromene-1,3(4H)-dione 

Relevant articles and documents

Isoquinolones: Part IV - Synthesis of 3-Methylisoquinolone-4-carboxylic Acids and Action of Ammonia and Aqueous Methyl Amine on 3-Methylisocoumarin-4-carboxylic Acid Esters

Ammonia reacts with 3-methylisocoumarin-4-carboxylic acid ester (II) on a boiling water-bath to give homophthalimide (III, R'=H) and 3-methylisoquinolone-4-carboxylic acid ester (IV) in nearly equal amounts.At room temperature ammonia reacts to give IV as the major product in good yield.Aq. methyl amine, however, reacts with II to give N-methylhomophthalimide (III, R'=Me) as the major product along with small amounts of compound VI (R1=Me) and some unchanged isocoumarin.Formation of the various products has been rationalised.