76812-37-8

Basic information

• Product Name: 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-(dimethylamino)ethyl ester
• CAS NO: 76812-37-8
• Molecular Formula: C23H25ClN2O4
• Molecular Weight: 428.915
• Mol File: 76812-37-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-(dimethylamino)ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-(dimethylamino)ethyl ester(76812-37-8)
• EPA Substance Registry System: 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-(dimethylamino)ethyl ester(76812-37-8)

Safety Data

• Hazardous Substances Data: 76812-37-8(Hazardous Substances Data)

Upstream product

• 17200-12-3 lithium 2-(dimethylamino)ethanolate 
• 53-86-1 [1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid 
• 108-01-0 2-(N,N-dimethylamino)ethanol 
• 78667-00-2 N,N'-Diisopropyl-O-(2-dimethylamino)-ethyl-isoharnstoff 

Downstream Products

• 53-86-1 [1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid 
• 121038-76-4 2-[[2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl]oxy]-N,N,N-trimethyl-ethanaminium iodide 

Relevant articles and documents

UNIQUE DUAL-ACTION THERAPEUTICS

A new family of therapeutics which provides a controlled-release delivery platform for non-steroidal anti-inflammatory agents on an ester or an ester-carbonate backbone is disclosed herein. These agents are reversible inhibitors of acetylcholinesterase and are thus useful for clinical conditions benefiting from inflammation suppression and cholinergic intervention. These compounds are of the general formula wherein n = 0, 1; X = C, Si, and N+ and NSAID = ibuprofen, naproxen, indomethacin and diclofenac. Other embodiments are also disclosed

Non Steroidal Antiinflammatory Agents. V. Basic Esters of Indometacin

The reaction of diisopropylcarbodiimid 1a with ethanolamines 2a, b affords isoureas 3a, b which in turn react with indometacin 4 to yield the title compounds 6a, b.The noncatalyzed reaction of 1a, b with 4 (also in the presence of 2) leads to the ureido-indometacines 8a, b.