76946-21-9

Basic information

• Product Name: (S)-2-(TETRAHYDRO-PYRAN-2-YLOXY)-PROPAN-1-OL
• Synonyms: (S)-2-(TETRAHYDRO-PYRAN-2-YLOXY)-PROPAN-1-OL;(2S)-2-[(Tetrahydro-2H-pyran-2-yl)oxy]-1-propanol;(2S)-2-[(Tetrahydro-2H-pyran-2-yl)oxy]propan-1-ol;(S)-2-(Tetrahydro-2-pyranoxy)-1-propanol;(S)-2-(Tetrahydro-2-pyranyloxy)-1-propanol;(S)-2-Tetrahydropyranyloxy-1-propanol;2-[(Tetrahydro-2H-pyran-2-yl)oxy]-1-propanolstereoisomer;2-(Tetrahydro-2H-pyran-2-yloxy)-1-propanol
• CAS NO: 76946-21-9
• Molecular Formula: C₈H₁₆O₃
• Molecular Weight: 160.21
• Mol File: 76946-21-9.mol
• Article Data: 25

Chemical Properties

• Boiling Point: 263℃
• Flash Point: 113℃
• Appearance: /
• Density: 1.04
• Refractive Index: 1.4542
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (S)-2-(TETRAHYDRO-PYRAN-2-YLOXY)-PROPAN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(TETRAHYDRO-PYRAN-2-YLOXY)-PROPAN-1-OL(76946-21-9)
• EPA Substance Registry System: (S)-2-(TETRAHYDRO-PYRAN-2-YLOXY)-PROPAN-1-OL(76946-21-9)

Safety Data

• Hazardous Substances Data: 76946-21-9(Hazardous Substances Data)

Usage

General Description

(S)-2-(Tetrahydro-pyran-2-yloxy)-propan-1-ol, also known as Tetrahydropyranyloxypropanol, is a chemical compound with the molecular formula C8H16O2. It is an alcohol derivative with a tetrahydropyran group attached to a propanol group. (S)-2-(TETRAHYDRO-PYRAN-2-YLOXY)-PROPAN-1-OL is commonly used as a protecting group in organic synthesis to selectively protect alcohols during chemical reactions and deprotection processes. It plays a crucial role in the protection of hydroxyl groups in synthetic chemistry and is widely used in the pharmaceutical and chemical industries for the production of various drugs and chemical compounds. Additionally, Tetrahydropyranyloxypropanol is also utilized as an intermediate in the production of flavor and fragrance compounds.

Upstream product

• 3539-40-0 Ethyl (S)-(-)-2-tetrahydropyran-2-yloxypropionate 
• 110-87-2 3,4-dihydro-2H-pyran 
• 73208-70-5 ethyl (2S)-2-(tetrahydropyran-2-yloxy)propionate 
• 151749-41-6 3-(3-Chloro-2-hydroxy-phenyl)-4-methyl-4H-pyrano[3,2-c]chromen-5-one 
• 153829-63-1 methyl (2S)-2-(tetrahydro-2H-pyran-2-yloxy)propanoate 
• 3539-40-0 ethyl 2-((tetrahydro-2H-pyran-2-yl)oxy)propanoate 

Downstream Products

• 85483-96-1 (2S)-1-benzyloxy-2-propanyl tetrahydropyran-2-yl ether 
• 61217-63-8 (S,S)-(+)-bis(2-hydroxypropyl) ether 
• 4254-15-3 (S)-1,2-Propanediol 
• 32464-98-5 (2S)-2-hydroxypropyl 4-methylbenzenesulfonate 
• 42274-61-3 (2S)-2-(tetrahydro-2H-pyran-2-yloxy)propyl 4-methylbenzenesulfonate 
• 42274-61-3 (S)-(-)-2-(tetrahydropyranyloxy)propyl p-toluenesulfonate 
• 76900-33-9 C₂₂H₄₂O₈ 
• 13807-91-5 (2S)-1-(benzyloxy)propan-2-ol 
• 1025975-08-9 1,3-bis(4'-tetrahydropyranyloxy-2-oxapentyl)-2,5-dimethoxybenzene 
• 103239-97-0 1-(benzyloxy)-4-<(S)-2-<(tetrahydro-2-pyranyl)oxy>propoxy>benzene 
• 143331-41-3 (2S,12S)-(-)-2,12-bis(tetrahydropyranyloxy)-7-trityl-7-aza-4,10-dioxatridecane 
• 131889-37-7 Methyl 4-<(S)-2-(tetrahydro-2-pyranoxy)propoxy>-benzoate 

Relevant articles and documents

BIARYL DERIVATIVES AS YAP/TAZ-TEAD PROTEIN-PROTEIN INTERACTION INHIBITORS

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; (I) a method for manufacturing said compound, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition comprising said compound.

Templated hierarchical self-assembly of poly(p-aryltriazole) foldamers

A biomimetic approach has been used for the templated self-assembly of a helical poly(para-aryltriazole) foldamer. The solvophobic folding process yields helices that further self-assemble into long nanotubes (see picture; scale bar: 100a nm). Constructs of controlled length and chirality can be generated by applying a poly(γ-benzyl-l-glutamate) scaffold at the appropriate assembly conditions, mimicking tobacco mosaic virus self-assembly. Copyright

Identification of absolute helical structures of aromatic multilayered oligo(m-phenylurea)s in solution

(Chemical Equation Presented) The oligomeric aromatic ureas bearing N,N′-dimethylated urea bonds such as 3 have aromatic multi-layered structure, based on the (cis,cis)-urea structure, and also have dynamic helical structure (all-R or all-S axis chirality) when the benzene rings are connected at the meta positions. The absolute helical structure of oligo(m-phenylurea)s were identified by the empirical and theoretical studies on the CD and vibrational CD (VCD) spectra. Thus, each enantiomer of the oligo(m-phenylurea)s 4 bearing a chiral N-2-(methoxyethoxyethoxy)propyl group were synthesized. Intense dispersion-type CD spectra of 4 were observed, which indicated the induction of handedness in the helical structure. In the VCD spectra of 4 in the film state, the signals due to the carbonyl and aromatic ring vibrations were seen with negative and positive values for compounds 4a and 4b, respectively. The calculations of both CD and VCD spectra of oligo(m-phenylurea)s 3 without any chiral N-substituent gave the same assignment about the axis chirality of 4. Thus, the absolute configurations of 4a and 4b are all-R and all-S structures, respectively. 2009 American Chemical Society.