76951-66-1Relevant articles and documents
Novel selectivity in carbohydrate reactions, IV: DABCO-mediated regioselective primary hydroxyl protection of carbohydrates
Gadakh, Bharat Kacheshwar,Patil, Premanand Ramrao,Malik, Satish,Kartha, K. P. Ravindranathan
experimental part, p. 2430 - 2438 (2009/12/03)
An efficient procedure for the regioselective tritylation of primary hydroxyl group of aldohexopyranosides and nucleosides using trityl chloride in the presence of 1,4-diazabicyclo[2.2.2]octane (DABCO) in dichloromethane has been developed. Subsequent acetylation of the tritylated products in the same pot has been made possible, thereby providing an efficient route to the fully protected carbohydrate derivatives that can be discriminated chemoselectively.
Alternative reagents for the tritylation of alcohols
Jyothi,Mahalingam,Ilangovan,Sharma
, p. 2091 - 2101 (2008/02/04)
Two new tritylation reagents [viz. p-methoxybenzyl trityl ether (p-MBTE) and prenyl trityl ether (PTE)] were prepared. These two new reagents were utilized efficiently for the tritylation of alcohols, using DDQ or 20 mol% DDQ-3 eq. Mn(OAc)3. Copyright Tay
p-Methoxybenzyl trityl ether (p-MBTE): A new and improved tritylating reagent
Sharma,Mahalingam,Prasad
, p. 1479 - 1481 (2007/10/03)
p-Methoxybenzyl trityl ether (p-MBTE), synthesized for the first time from trityl chloride and p-methoxybenzyl alcohol, is utilized as a tritylating agent for a variety of alcohols, under neutral conditions, in 10-30 min. and excellent yields.