77-19-0 Usage
Description
Dicycloverine, also known as dicyclomine hydrochloride, is an anticholinergic medication derived from the ester resulting from the formal condensation of 1-cyclohexylcyclohexanecarboxylic acid with 2-(diethylamino)ethanol. It is characterized by its anticholinergic properties and is used to treat or prevent muscle spasms in the gastrointestinal tract, particularly those associated with irritable bowel syndrome.
Uses
Used in Pharmaceutical Industry:
Dicycloverine is used as an anticholinergic agent for treating or preventing muscle spasms in the gastrointestinal tract, particularly those associated with irritable bowel syndrome. It works by blocking the action of acetylcholine, a neurotransmitter that can cause muscle contractions, thus providing relief from spasms and discomfort.
Brand names for dicycloverine include Bentyl (Axcan Scandipharm), Abacid plus, Ametil, Babypasmil, Babyspasmil, Baycyclomine, Benacol, Colix, Cyclobex, Cyclocen, Diarrest, Diclophen, Eatongel, Esentil, Fomulex, Formulex, Gastrosilane, Icramin, Incramin, Incron, Inctacol-c, Isospamex, Kolanticon, Lagasediv, Menospasm, Merbantal, Neoquess, Nomocramp, Notensyl, Or-tyl, Pamin, Panakiron, Prinel, Protylol, Sawamin, Spactil, Spasmoban, Spastil, Tarestin, and Viscerol.
Therapeutic Function
Spasmolytic
World Health Organization (WHO)
Dicycloverine, an anticholinergic agent with antispasmodic and
local anaesthetic activity, was introduced in 1952 for treatment of functional
conditions involving smooth muscle of the gastrointestinal tract. Its use in the
treatment of colic in infants under six months of age has been associated with
irritability and restlessness, convulsions and apnoea which has led the major
manufacturer to issue revised global prescribing information in 1985
contraindicating the use of dicycloverine in this age group. Subsequently
restrictive regulatory action directed to other available brands of this drug was taken in several countries. Preparations containing dicycloverine remain available
in at least ten major markets.
Check Digit Verification of cas no
The CAS Registry Mumber 77-19-0 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 7 and 7 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 77-19:
(4*7)+(3*7)+(2*1)+(1*9)=60
60 % 10 = 0
So 77-19-0 is a valid CAS Registry Number.
InChI:InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3
