77-38-3 Usage
Description
Chlorphenoxamine, also known as Chlor-Trimeton, is a medication belonging to the class of antihistamines. It is primarily used to treat symptoms caused by the release of histamine in the body, such as allergic reactions and colds. Chlorphenoxamine works by blocking the action of histamine, providing relief from itching, swelling, and other discomforts associated with histamine release.
Uses
Used in Pharmaceutical Industry:
Chlorphenoxamine is used as an antihistaminic agent for the treatment of allergic reactions and colds. It is effective in relieving symptoms such as itching, swelling, and runny nose caused by histamine release in the body.
Used in Antimicrobial Applications:
Chlorphenoxamine is used as a treatment for antibacterial infections. It helps in reducing the severity and duration of symptoms associated with bacterial infections, such as cough, cold, and sore throat. However, it is important to note that Chlorphenoxamine does not kill bacteria directly but helps in managing the symptoms and supporting the body's immune response to fight the infection.
Check Digit Verification of cas no
The CAS Registry Mumber 77-38-3 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 7 and 7 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 77-38:
(4*7)+(3*7)+(2*3)+(1*8)=63
63 % 10 = 3
So 77-38-3 is a valid CAS Registry Number.
InChI:InChI=1/C18H22ClNO/c1-18(21-14-13-20(2)3,15-7-5-4-6-8-15)16-9-11-17(19)12-10-16/h4-12H,13-14H2,1-3H3
77-38-3Relevant articles and documents
ORGANOMANGANESE (II) REAGENTS XIV: A SHORT AND EFFICIENT SYNTHESIS OF DIASTEREOISOMERIC (+/-)-α-BISABOLOLS AND (+/-)-CHLORPHENOXAMINE
Cahiez, Gerard,Rivas-Enterrios, Jose,Clery, Patrick
, p. 3659 - 3662 (2007/10/02)
Diastereomeric (+/-)-α-bisabolols (7), a sesquiterpenoid alcohol, and (+/-)-chlorphenoxamine (12), an antihistamine, have been prepared in excellent yields.Both these short and convenient syntheses involve as a key step the one-pot elaboration of a dissymetrical tertiary alcohol via an organomanganese reagent (5 to 7 and 9 to 10 respectively).
