77-42-9 Usage
Description
[1S-[1alpha,2alpha(Z),4alpha]]-2-methyl-5-(2-methyl-3-methylenebicyclo[2.2.1]hept-2-yl)-2-penten-1-ol, also known as (Z)-β-Santalol, is a key component of sandalwood oil. It is a naturally occurring sesquiterpene alcohol with a unique molecular structure and a distinct aroma profile.
Uses
Used in Fragrance Industry:
(Z)-β-Santalol is used as a key ingredient in the fragrance industry for its unique and pleasant aroma. It is widely used in perfumes, colognes, and other scented products to provide a long-lasting and sophisticated scent.
Used in Skincare Applications:
(Z)-β-Santalol is used as an active ingredient in skincare products to suppress lipopolysaccharide-stimulated cytokine/chemokine production in skin cells. This helps in reducing inflammation and promoting skin health.
Used in Aromatherapy:
(Z)-β-Santalol is used in aromatherapy for its calming and soothing properties. It is believed to have a positive impact on mood and stress levels, promoting relaxation and well-being.
Used in Cosmetic Industry:
(Z)-β-Santalol is used in the cosmetic industry for its unique scent and skin-friendly properties. It is incorporated into various cosmetic products such as creams, lotions, and body oils to provide a pleasant fragrance and improve skin health.
Used in Flavor Industry:
(Z)-β-Santalol can also be used in the flavor industry to impart a unique and pleasant taste to food and beverage products. Its distinct aroma profile makes it suitable for use in gourmet foods, beverages, and confectionery items.
Check Digit Verification of cas no
The CAS Registry Mumber 77-42-9 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 7 and 7 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 77-42:
(4*7)+(3*7)+(2*4)+(1*2)=59
59 % 10 = 9
So 77-42-9 is a valid CAS Registry Number.
InChI:InChI=1/C15H24O/c1-11(10-16)5-4-8-15(3)12(2)13-6-7-14(15)9-13/h5,13-14,16H,2,4,6-10H2,1,3H3/b11-5-/t13-,14-,15+/m1/s1
77-42-9Relevant articles and documents
Hayashi et al.
, p. 1824,1825 (1965)
The synthesis of (Z)-trisubstituted allylic alcohols by the selective 1,4-hydrogenation of dienol esters: Improved synthesis of (-)-β-santalol
Fehr, Charles,Magpantay, Iris,Vuagnoux, Magali,Dupau, Philippe
experimental part, p. 1257 - 1260 (2011/04/16)
(E)-Trisubstituted allylic alcohols are commonly prepared from the corresponding (E)-enals, themselves readily accessible by a simple aldol condensation reaction. We demonstrate that these very same (E)-enals can be converted into (Z)-trisubstituted allylic acetates (and thus alcohols) by a ruthenium-catalyzed 1,4-hydrogenation of the corresponding dienol acetates. This simple solution to a long-lasting problem was applied to an industrially feasible synthesis of (-)-β-santalol.
Total Syntheses, Optical Rotations and Fragrance Properties of Sandalwood Constituents: (-)-(Z)- and (-)-(E)-β-Santalol and Their Enantiomers, ent-β-Santalene
Krotz, Achim,Helmchen, Guenter
, p. 601 - 610 (2007/10/02)
Enantiomerically pure 5-norbornene-2-carboxylic acids 4, obtained by asymmetric Diels-Alder additions, were oxidatively degraded to (+)- and (-)-2-norbornanone and (+)- and (-)-3-methyl-2-norbornanone which were converted into the title compounds by stereoselective alkylations, subsequent cis- and trans-selective Wittig reactions and reductions.Precise optical rotations were determined for (Z)- and (E)-β-santalol (1 and 2) and β-santalene (3a) which were obtained by total synthesis and, in addition, by isolation from East Indian sandalwood oil. - Key Words: Sandalwood oil / Fragrances / Stereoselective synthesis / β-Santalene, pure, isolation / Enantiomers, fragrance properties
