77-70-3 Usage
Description
Ethyl 2-hydroxy-2-methylbutyrate is a clear, colorless liquid with a caramelized, nutty aroma. It has a medium strength odor and is recommended to be smelled in a 10.00% solution or less.
Uses
Used in Flavor and Fragrance Industry:
Ethyl 2-hydroxy-2-methylbutyrate is used as a flavoring agent for its caramel nutty aroma. It is added to various food products to enhance their taste and aroma.
Used in Perfumery:
Ethyl 2-hydroxy-2-methylbutyrate is used as a fragrance ingredient in perfumes and colognes to provide a unique and pleasant scent.
Used in Cosmetics:
Ethyl 2-hydroxy-2-methylbutyrate is used in cosmetics as a scent enhancer to improve the overall fragrance of the product.
Used in Beverage Industry:
Ethyl 2-hydroxy-2-methylbutyrate is used as a flavoring agent in the beverage industry to add a caramel nutty taste to drinks such as soft drinks, alcoholic beverages, and fruit juices.
Used in Confectionery:
Ethyl 2-hydroxy-2-methylbutyrate is used in confectionery products such as chocolates, candies, and baked goods to provide a caramel nutty flavor and aroma.
Check Digit Verification of cas no
The CAS Registry Mumber 77-70-3 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 7 and 7 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 77-70:
(4*7)+(3*7)+(2*7)+(1*0)=63
63 % 10 = 3
So 77-70-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H14O3/c1-4-7(3,9)6(8)10-5-2/h9H,4-5H2,1-3H3
77-70-3Relevant articles and documents
Mechanism and scope of salen bifunctional catalysts in asymmetric aldehyde and α-ketoester alkylation
Fennie, Michael W.,DiMauro, Erin F.,O'Brien, Erin M.,Annamalai, Venkatachalam,Kozlowski, Marisa C.
, p. 6249 - 6265 (2007/10/03)
Metal complexes of C2-symmetric Lewis acid/Lewis base salen ligands provide bifunctional activation resulting in rapid rates in the enantioselective addition of diethylzinc to aldehydes (up to 92% ee). Further experiments probed the reactivity of the individual Lewis acid and Lewis base components of the catalyst and established that both moieties are essential for asymmetric catalysis. These catalysts are also effective in the asymmetric addition of diethylzinc to α-ketoesters. This finding is significant because α-ketoesters alone serve as their own ligands to accelerate racemic 1,2-carbonyl addition of Et2Zn and racemic carbonyl reduction. The latter proceeds via a metalloene pathway, and often accounts for the predominant product. Singular Lewis acid catalysts do not accelerate enantioselective 1,2-addition over these two competing paths. The bifunctional amino salen catalysts, however, rapidly provide enantioenriched 1,2-addition products in excellent yield, complete chemoselectivity, and good enantioselectivity (up to 88% ee). A library of the bifunctional amino salens was synthesized and evaluated in this reaction. The utility of the α-ketoester method has been demonstrated in the synthesis of an opiate antagonist.
