771-91-5

Basic information

• Product Name: (1S,2S)-2-AMINO-1-(4-HYDROXYPHENYL)PROPANE-1-OL
• Synonyms: (1S,2S)-2-AMINO-1-(4-HYDROXYPHENYL)PROPANE-1-OL;(-)-4-Hydroxynorephedrin;(1R,2S)-2-Amino-1-(4-hydroxyphenyl)propane-1-ol
• CAS NO: 771-91-5
• Molecular Formula: C₉H₁₃NO₂
• Molecular Weight: 167.20502
• Mol File: 771-91-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 165-166 ºC
• Boiling Point: 357.9±27.0 °C(Predicted)
• Appearance: /
• Density: 1.198
• PKA: 9.96±0.26(Predicted)
• CAS DataBase Reference: (1S,2S)-2-AMINO-1-(4-HYDROXYPHENYL)PROPANE-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2S)-2-AMINO-1-(4-HYDROXYPHENYL)PROPANE-1-OL(771-91-5)
• EPA Substance Registry System: (1S,2S)-2-AMINO-1-(4-HYDROXYPHENYL)PROPANE-1-OL(771-91-5)

Safety Data

• Hazardous Substances Data: 771-91-5(Hazardous Substances Data)

Usage

General Description

(1S,2S)-2-AMINO-1-(4-HYDROXYPHENYL)PROPANE-1-OL is a chemical compound with the molecular formula C9H13NO2. It belongs to the class of compounds known as phenylpropanoid derivatives. (1S,2S)-2-AMINO-1-(4-HYDROXYPHENYL)PROPANE-1-OL is a chiral molecule, meaning it exists in two mirror-image forms. It consists of a central carbon atom bonded to a hydroxyl group, an amino group, and a phenyl group. (1S,2S)-2-AMINO-1-(4-HYDROXYPHENYL)PROPANE-1-OL has potential applications in pharmaceuticals, as it may exhibit biological activities due to the presence of the phenyl and amino groups in its structure.

Upstream product

• 552-85-2 (+/-)-p-Hydroxy-norephedrin 
• 552-85-2 p-hydroxynorepherdine 
• 635304-39-1 (2S)-1-[4-(benzyloxy)phenyl]-2-[((1R)-phenylethyl)amino]-1-propanone methanesulfonate 
• 635304-65-3 (2S)-1-(4-hydroxyphenyl)-2-[((1R)-phenylethyl)amino]-1-propanone 
• 635304-44-8 (1R, 2S)-1-[4-(benzyloxy)phenyl]-2-[((1R)-phenylethyl)amino]-1-propanol 
• 104-88-1 4-chlorobenzaldehyde 
• 25070-02-4 (1RS,2RS)-2-dibenzylamino-1-(4-benzyloxy-phenyl)-propan-1-ol 
• 100-46-9 benzylamine 
• 103-49-1 dibenzylamine 

Downstream Products

• 395-28-8 (1RS,2RS)-1-(4-hydroxy-phenyl)-2-((Ξ)-β-phenoxy-isopropylamino)-propan-1-ol 
• 395-28-8 (+/-)-1-<4-Hydroxyphenyl>-2-<1-methyl-2-phenoxyaethylamino>-propan-1-ol 
• 395-28-8 (1RS,2SR)-1-(4-hydroxy-phenyl)-2-((RS)-β-phenoxy-isopropylamino)-propan-1-ol 
• 17885-18-6 (1RS,2SR)-1-acetoxy-1-(4-acetoxy-phenyl)-2-acetylamino-propane 
• 108746-15-2 (1RS,2SR)-1-(4-hydroxy-phenyl)-2-isopropylamino-propan-1-ol 
• 395-29-9 (+)-Isoxsuprin 
• 1926-72-3 (+/-)-4-Hydroxynorephedrin 
• 552-85-2 4-((1R,2S)-2-amino-1-hydroxypropyl)phenol 
• 1027916-20-6 (4-{2-[(1S,2R)-2-Hydroxy-2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-phenylamino)-acetic acid ethyl ester 
• 227467-79-0 ethyl N-[4-[2-[[(1S, 2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-methyl-ethyl]amino]ethyl]phenyl]-N-methylaminoacetate 

Relevant articles and documents

Method for synthesizing ritodrine hydrochloride

The invention discloses a method for synthesizing ritodrine hydrochloride. The method comprises that p-chlorobenzaldehyde and pyruvic acid as substrates undergo a catalytic reaction, the product is purified to form (R)-1-(4-chlorophenyl)-1-hydroxypropane-2-one, the (R)-1-(4-chlorophenyl)-1-hydroxypropane-2-one and ammonium formate as substrates undergo a catalytic reaction, the product is purifiedto form (1R, 2S)-2-amino-1-(4-chlorophenyl)-1-propanol, the (1R, 2S)-2-amino-1-(4-chlorophenyl)-1-propanol and LiOH. H2O undergo a reaction to produce 4-((1R, 2S)-2-amino-1-hydroxypropyl)phenol and 4-((1R, 2S)-2-amino-1-hydroxypropyl)phenol and 4-(2-chloroethanol)phenol undergo a reaction to produce ritodrine hydrochloride. The method realizes a low cost, utilizes mild reaction conditions and issuitable for industrial production.

PHENOL DERIVATIVES AND METHOD OF USE THEREOF

The present invention provides novel phenol derivatives represented by the formula: wherein the carbon atom marked with (S) represents a carbon atom in S configuration; Z represents the group represented by the formula: or the formula: wherein the carbon

Antimitotic agents. Chiral isomers of ethyl [5-amino-1,2-dihydro-3-(4- hydroxyphenyl)-2-methylpyrido[3,4-b]pyrazin-7-yl]carbamate

Metabolism studies with ethyl [5-amino-1,2-dihydro-2-methyl-3- phenylpyrido[3,4-b]pyrazin-7-yl]carbamate (1) in mice were reported previously to give a hydroxylated metabolite, which was methylated to give a methoxy derivative. The metabolite and its deri