77120-93-5

Basic information

• Product Name: (2RS,3RS,4SR)-4-benzylamino-2-methyl-6-oxotetrahydropyran-3-carboxylic-acid hydrochloride
• CAS NO: 77120-93-5
• Molecular Weight: 299.754
• Mol File: 77120-93-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2RS,3RS,4SR)-4-benzylamino-2-methyl-6-oxotetrahydropyran-3-carboxylic-acid hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (2RS,3RS,4SR)-4-benzylamino-2-methyl-6-oxotetrahydropyran-3-carboxylic-acid hydrochloride(77120-93-5)
• EPA Substance Registry System: (2RS,3RS,4SR)-4-benzylamino-2-methyl-6-oxotetrahydropyran-3-carboxylic-acid hydrochloride(77120-93-5)

Safety Data

• Hazardous Substances Data: 77120-93-5(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 108908-43-6 ((2S,3R)-3-Acetyl-1-benzyl-4-oxo-azetidin-2-yl)-acetonitrile 
• 87231-36-5 [(2S,3R)-1-Benzyl-3-(2-methyl-[1,3]dioxolan-2-yl)-4-oxo-azetidin-2-yl]-acetonitrile 
• 90210-81-4 1-benzyl-4-cyanomethyl-3-(1'-hydroxyethyl)azetidin-2-one 
• 77120-91-3 (E)-2-Acetyl-3-benzylamino-pent-2-enedioic acid diethyl ester 
• 77120-90-2 3-Benzylamino-2-pentenedioic acid diethyl ester 
• 77120-92-4 (2R,3S)-3-Benzylamino-2-((R)-1-hydroxy-ethyl)-pentanedioic acid diethyl ester 

Downstream Products

• 79543-87-6 4-[(2S,3R)-3-((S)-1-Formyloxy-ethyl)-4-oxo-azetidin-2-yl]-3-oxo-butyric acid 4-nitro-benzyl ester 
• 64067-13-6 (5R,6S)-6-((R)-1-Hydroxy-ethyl)-3-[2-(4-nitro-benzyloxycarbonylamino)-ethylsulfanyl]-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 77120-96-8 benzyl -4-oxoazetidin-2-yl> acetate 
• 74288-40-7 (2S,5S,6R)-6-((S)-1-Hydroxy-ethyl)-3,7-dioxo-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 4-nitro-benzyl ester 

Relevant articles and documents

Simple and Condensed β-Lactams. Part 7. Side Chain Extension of Some Azetidin-2-one Derivatives, and the Formation of Melillo's Lactone, a Strategic Intermediate in the Total Synthesis of Thienamycin, from 3-Acetyl-1-benzyl-4-cyanomethylazetidin-2-one

The oxoazetidinecarboxylic acids (2a) and (2b) and the homologous acid (8b) were converted by treatment of their chlorides with ethyl diazoacetate into the diazo esters (4a, b), and (1Ob), respectively.Irradiation of the diazo ester (4b) afforded the diet