77133-27-8

Basic information

• Product Name: 4-methoxythiophene-2-carboxylic acid
• Synonyms: 4-methoxythiophene-2-carboxylic acid
• CAS NO: 77133-27-8
• Molecular Formula: C6H6O3S
• Molecular Weight: 158
• Mol File: 77133-27-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-methoxythiophene-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methoxythiophene-2-carboxylic acid(77133-27-8)
• EPA Substance Registry System: 4-methoxythiophene-2-carboxylic acid(77133-27-8)

Safety Data

• Hazardous Substances Data: 77133-27-8(Hazardous Substances Data)

Upstream product

• 40748-90-1 4-hydroxythiophene-2-carboxylic acid 
• 77-78-1 dimethyl sulfate 
• 5118-05-8 4-Methoxythiophen-2-carbonsaeuremethylester 
• 16694-18-1 4-bromo-thiophene-2-carboxylic acid 
• 62224-16-2 4-bromothiophene-2-carboxylic acid methyl ester 
• 6324-10-3 4,5-Dibromo-thiophene-2-carboxylic acid 
• 17573-92-1 3-methoxy-thiophene 
• 109-72-8 n-butyllithium 
• 67-56-1 methanol 
• 124-41-4 sodium methylate 

Downstream Products

• 128995-59-5 4-methoxy-2-thiophenecarbonyl chloride 

Relevant articles and documents

An Analysis of 13C Nuclear Magnetic Resonance Substituent Chemical Shifts in 4- and 5-Substituted Thiophene-2-carboxylic Acids by Linear Free Energy Relationships

The 13C n.m.r. chemical shifts of some 4- and 5-substituted thiophene-2-carboxylic acids and of the corresponding anions have been measured in methanol.The observed substituent chemical shifts have been compared with the calculated values and then analysed according to single and dual substituent parameter linear free energy relationships.The results have been rationalized in terms of separate resonance and inductive contributions of substituent effects.The resonance term has shown that no conjugation occurs between the ring and the carboxy group.

Phosphorylamides, their preparation and use

A phosphorylamide derivative represented by the general formula (I): STR1 wherein R represents an amino group that may be substituted, or a salt thereof, possesses potent antibacterial activity against Helicobacter bacterium, especially Helicobacter pylori, and is useful for prevention or treatment of digestive diseases caused by Helicobacter bacterium, solely or in combination with an antacid or an acid secretion inhibitor.