77148-46-0

Basic information

• Product Name: C₁₂H₁₃N₂S⁽¹⁺⁾*ClH*Cl^(1-)
• Synonyms: C₁₂H₁₃N₂S⁽¹⁺⁾*ClH*Cl^(1-)
• CAS NO: 77148-46-0
• Molecular Weight: 289.229
• Mol File: 77148-46-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₂H₁₃N₂S⁽¹⁺⁾*ClH*Cl^(1-)(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₁₃N₂S⁽¹⁺⁾*ClH*Cl^(1-)(77148-46-0)
• EPA Substance Registry System: C₁₂H₁₃N₂S⁽¹⁺⁾*ClH*Cl^(1-)(77148-46-0)

Safety Data

• Hazardous Substances Data: 77148-46-0(Hazardous Substances Data)

Upstream product

• 3099-31-8 nicotinyl chloride 
• 2044-27-1 1-methyl-2-pyridinethione 

Relevant articles and documents

Anti-ulcer and gastric antisecretory activity of a series of thioethers and related sulphoxides

A series of thioethers containing a pyridinium moiety were prepared and tested for gastric antisecretory and anti-ulcer activity. Following initial screening two compounds 2-(3-chlorobenzylthio)-1-methylpyridinium chloride and 2-(2-fluorobenzylthio)-1-methylpyridinium chloride were investigated further. By modification of substituent groups some separation of anti-ulcer and antisecretory activity was achieved. Subsequently it was found that the pyridinium moiety could be replaced and a number of related thioethers and sulphoxides were synthesised and were also found to be active. A wide range of structural variations were found to be possible with retention of activity.