7716-87-2

Basic information

• Product Name: (5-Chloro-2-nitrophenyl)phenylmethanone
• CAS NO: 7716-87-2
• Molecular Formula: C₁₃H₈ClNO₃
• Molecular Weight: 261.664
• Mol File: 7716-87-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (5-Chloro-2-nitrophenyl)phenylmethanone(CAS DataBase Reference)
• NIST Chemistry Reference: (5-Chloro-2-nitrophenyl)phenylmethanone(7716-87-2)
• EPA Substance Registry System: (5-Chloro-2-nitrophenyl)phenylmethanone(7716-87-2)

Safety Data

• Hazardous Substances Data: 7716-87-2(Hazardous Substances Data)

Usage

Description

(5-Chloro-2-nitrophenyl)phenylmethanone, with the molecular formula C13H8ClNO3, is a yellow solid chemical compound. It is recognized for its potential as an anti-inflammatory and antipyretic agent, and it serves as a crucial intermediate in the synthesis of various pharmaceuticals and agrochemicals. The presence of a nitro group in its structure endows it with high reactivity, making it a versatile building block for a broad spectrum of organic compounds. Its utility extends across the pharmaceutical and chemical industries due to its diverse applications.

Uses

Used in Pharmaceutical Industry:
(5-Chloro-2-nitrophenyl)phenylmethanone is used as an intermediate for the synthesis of various pharmaceuticals, leveraging its reactivity and structural properties to create a range of medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical sector, (5-Chloro-2-nitrophenyl)phenylmethanone is utilized as a building block for the development of different agrochemicals, contributing to its role in the production of substances that protect crops and enhance agricultural productivity.
Used as an Anti-inflammatory Agent:
(5-Chloro-2-nitrophenyl)phenylmethanone is used as an anti-inflammatory agent, where its potential to alleviate inflammation is harnessed for therapeutic purposes.
Used as an Antipyretic Agent:
(5-Chloro-2-nitrophenyl)phenylmethanone is also employed as an antipyretic agent, helping to reduce fever and associated symptoms in patients.
Used in Organic Synthesis:
(5-Chloro-2-nitrophenyl)phenylmethanone is used as a building block in organic synthesis, where its reactivity, particularly due to the nitro group, is exploited in various chemical reactions such as nucleophilic aromatic substitution and reduction reactions, leading to the creation of a diverse array of organic compounds.

Upstream product

• 24400-58-6 6-chloro-3-phenyl-2,1-benzisoxazole 

Downstream Products

• 64133-88-6 2-(3-Benzoyl-4-nitro-phenyl)-2-phenyl-butyronitrile 
• 42872-30-0 alpha-(m-benzoylphenyl)propionitrile 
• 22071-15-4 ketoprofen 
• 719-64-2 5-chloro-3-phenylanthranil 
• 64133-82-0 2.5-Dibenzoyl-4-chloranilin 
• 64133-87-5 2-(3-Benzoyl-4-nitro-phenyl)-2-phenyl-propionitrile 
• 146470-15-7 C₁₄H₁₂ClN₅O₂*ClH 
• 64133-90-0 (5-chloro-3-phenyl-benzo[c]isoxazol-7-yl)-phenyl-methanone 
• 62597-53-9 2,2'-Dibenzoyl-4,4'-dichlor-azoxybenzol 

Relevant articles and documents

Ketoprofen intermediate as well as preparation method and application thereof

The invention relates to the field, of medicine synthesis, in particular to a ketoprofen intermediate and a preparation method and application. thereof to prepare the ketoprofen, reaction formula by sequentially performing an oxidation reaction, substitution reaction, deamination, deamination and an acidic hydrolysis reaction after formation of the isoxazole compound, by a Diels,Alder reaction with a phenylacetic acid by. a Diels :Alder reaction of a phenylacetic acid. In-flight, X2 or. Ortho or para, R to nitro or amino group1 - COCONR4 R5 , COX1 , COOR2 Or - CNCNCNR2 , R3 , R4 , R5 , R6 The same or different is H or C. 1 - C6 Alkyl, X1 , X2 The same or different is F, Cl, Br or I.