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77180-80-4

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77180-80-4 Usage

General Description

5-Fluorouridine is a synthetic analog of the nucleoside uridine that has been modified with a fluorine atom at the 5-position. It is widely used in research as a potential anticancer agent due to its ability to inhibit RNA synthesis and disrupt nucleic acid metabolism. 5-Fluorouridine has been shown to exhibit antitumor activity and has been investigated for its potential use in the treatment of various types of cancer. It has also been utilized as a biochemical tool for studying RNA function and metabolism. Additionally, 5-Fluorouridine has shown potential as a radiosensitizer, enhancing the effectiveness of radiotherapy in cancer treatment. Despite its promising bioactivity, the compound's use in clinical settings is still under investigation, and further studies are needed to fully understand its mechanisms of action and potential therapeutic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 77180-80-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,1,8 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 77180-80:
(7*7)+(6*7)+(5*1)+(4*8)+(3*0)+(2*8)+(1*0)=144
144 % 10 = 4
So 77180-80-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H11FN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m0/s1

77180-80-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Fluorouridine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:77180-80-4 SDS

77180-80-4Downstream Products

77180-80-4Relevant articles and documents

Preparation, antibacterial effects and enzymatic degradation of 5-fluorouracil nucleosides

Schwarz,Cech,Holy,Skoda

, p. 3217 - 3230 (2007/10/02)

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