77200-24-9

Basic information

• Product Name: 1-(2-CHLOROETHYL)PYRROLE
• Synonyms: 1-(2-CHLOROETHYL)PYRROLE;Chloroethylpyrrole;1-(2-Chloroethyl)-1H-pyrrole;1H-Pyrrole, 1-(2-chloroethyl)-
• CAS NO: 77200-24-9
• Molecular Formula: C₆H₈ClN
• Molecular Weight: 129.59
• Product Categories: Functional Materials;Pyrroles (for Conduting Polymer Research);Reagents for Conducting Polymer Research;pyrrole
• Mol File: 77200-24-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 84 °C / 20mmHg
• Flash Point: 65.576 °C
• Appearance: /
• Density: 1,13 g/cm3
• Vapor Pressure: 0.985mmHg at 25°C
• Refractive Index: 1.5170-1.5200
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: -3.55±0.70(Predicted)
• CAS DataBase Reference: 1-(2-CHLOROETHYL)PYRROLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-CHLOROETHYL)PYRROLE(77200-24-9)
• EPA Substance Registry System: 1-(2-CHLOROETHYL)PYRROLE(77200-24-9)

Safety Data

• Statements: 36/37/38
• Safety Statements: 36/37/39
• Hazardous Substances Data: 77200-24-9(Hazardous Substances Data)

Usage

General Description

1-(2-Chloroethyl)pyrrole is a chemical compound with the molecular formula C6H8ClN. It is a derivative of pyrrole, a five-membered aromatic heterocycle. The compound contains a chloroethyl group attached to one of the carbon atoms in the pyrrole ring. 1-(2-CHLOROETHYL)PYRROLE has potential applications in the field of organic synthesis and medicinal chemistry. It may also be used as a building block for the synthesis of more complex organic molecules. Additionally, the presence of the chloroethyl group makes it a potentially useful reagent for the introduction of this functionality into other organic compounds. Due to its chemical structure and reactivity, 1-(2-chloroethyl)pyrrole has potential uses in pharmaceutical and agrochemical industries. However,

InChI:InChI=1/C6H8ClN/c7-3-6-8-4-1-2-5-8/h1-2,4-5H,3,6H2

Upstream product

• 80-41-1 2-chloroethyl tosylate 
• 16199-06-7 potassium pyrrolide 
• 696-59-3 cis,trans-2,5-dimethoxytetrahydrofuran 
• 870-24-6 2-chloroethanamine hydrochloride 
• 109-97-7 pyrrole 
• 107-06-2 1,2-dichloro-ethane 

Downstream Products

• 131727-07-6 N-(phenyl)-N-[1-(2-(1H-pyrrol-1-yl)ethyl)-4-methoxymethyl-4-piperidinyl]propanamide 
• 131727-05-4 N-(phenyl)-N-[1-(2-(1H-pyrrol-1-yl)ethyl)-4-methoxycarbonyl-4-piperidinyl]propanamide 
• 1392291-33-6 (4-isopropoxy-3-methoxyphenyl)(2'-methyl-6'-(trifluoromethyl)-3',4'-dihydro-2'H-spiro[piperidine-4,1'-pyrrolo[1,2-a]pyrazine]-1-yl)methanone 
• 100911-22-6 N-methyl-2-pyrrol-1-yl-ethanamine 
• 1443120-54-4 2-(4-propoxyphenyl)-4-[2-(1H-pyrrol-1-yl)ethoxy]quinoline 

Relevant articles and documents

A stimulus-responsive poly-pyrrole nano tube targeted drug carrier and its preparation method

The invention provides a stimulus-response type polypyrrole nanotube targeting drug carrier and a preparation method. A titanium dioxide nanotube array or a porous anodic alumina array serves as a template, and a polypyrrole nanotube is prepared through chemical vapor deposition; beta-cyclodextrin and a tube opening of a polypyrrole nanotube are connected through stimulus response type sensitive bonds such as acyl hydrazone bonds and disulfide bonds, and medicine can be blocked in the nanotube and released out in the faintly acid and reducibility environments; one end of a polyethylene glycol chain is connected with a folic acid targeted molecule, the other end of the polyethylene glycol chain is connected with an adamantane head base, the adamantane head base is linked up to a beta-cyclodextrin hydrophobic cavity through host and guest envelope, and folic acid molecules recognize tumor cells through a receptor-ligand medium. The stimulus-response type polypyrrole nanotube targeting drug carrier prepared through the method is uniform in particle diameter size distribution, controllable in appearance, stable in product, simple in synthesis process, low in cost and suitable for mass production.

PYRROLOPYRAZINE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS

The invention relates to pyrrolopyrazine-spirocyclic piperidine amide compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

Synthesis of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids and homologous pyridine and azepine analogues thereof

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