77262-39-6

Basic information

• Product Name: 4-(TRIFLUOROACETAMIDO)PYRIDINE
• Synonyms: 4-(TRIFLUOROACETAMIDO)PYRIDINE;4-(TRIFLUOROACETAMIDO)PYRIDINE, 97% MIN.;N-(Pyridin-4-yl)-2,2,2-trifluoroacetamide;2,2,2-Trifluoro-N-4-pyridinyl-acetaMide;2,2,2-Trifluoro-N-pyridin-4-yl-acetamide;Acetamide,2,2,2-trifluoro-N-4-pyridinyl-
• CAS NO: 77262-39-6
• Molecular Formula: C7H5F3N2O
• Molecular Weight: 190.12
• Product Categories: Amines;Aromatics
• Mol File: 77262-39-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 273.2°C at 760 mmHg
• Flash Point: 119°C
• Appearance: /
• Density: 1.438g/cm³
• Vapor Pressure: 0.00582mmHg at 25°C
• Refractive Index: 1.503
• Solubility: Acetone, Methanol
• CAS DataBase Reference: 4-(TRIFLUOROACETAMIDO)PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(TRIFLUOROACETAMIDO)PYRIDINE(77262-39-6)
• EPA Substance Registry System: 4-(TRIFLUOROACETAMIDO)PYRIDINE(77262-39-6)

Safety Data

• Hazardous Substances Data: 77262-39-6(Hazardous Substances Data)

Usage

Chemical Properties

Light Brown Solid

Uses

2,2,2-Trifluoro-N-4-pyridinyl-acetamide (cas# 77262-39-6) is a compound useful in organic synthesis.

InChI:InChI=1/C7H5F3N2O/c8-7(9,10)6(13)12-5-1-3-11-4-2-5/h1-4H,(H,11,12,13)

Upstream product

• 504-24-5 4-aminopyridine 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 74415-04-6 p-<(Trifluoroethyl)amino>pyridine 

Relevant articles and documents

Quinolone Antibacterials: Preparation and Activity of Bridged Bicyclic Analogues of the C7-Piperazine

A series of quinolone and naphthyridine antibacterial agents possessing as the C7-heterocycle bicyclic 2,5-diazabicycloalkanes, where n = 2, 3 and m = 1, 2, and a series including 4-aminopiperidine and 3-amino-8-azabicyclooctanes have been prepared and evaluated in vitro and in vivo for antibacterial activity against a variety of Gramm-negative and Gramm-positive organisms.These compounds were also tested against the target enzyme bacterial DNA gyrase.All the examples investigated are nearly equipotent with the parent 7-piperazinyl analogues.Only endo-7-(3-amino-8-azabicyclooct-8-yl) -1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid displays activity that surpasses that of the piperazine parent.