77445-12-6

Basic information

• Product Name: [2-(4-Fluoro-phenyl)-1H-indol-3-ylmethyl]-dimethyl-amine
• Synonyms: [2-(4-Fluoro-phenyl)-1H-indol-3-ylmethyl]-dimethyl-amine
• CAS NO: 77445-12-6
• Molecular Weight: 268.334
• Mol File: 77445-12-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [2-(4-Fluoro-phenyl)-1H-indol-3-ylmethyl]-dimethyl-amine(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(4-Fluoro-phenyl)-1H-indol-3-ylmethyl]-dimethyl-amine(77445-12-6)
• EPA Substance Registry System: [2-(4-Fluoro-phenyl)-1H-indol-3-ylmethyl]-dimethyl-amine(77445-12-6)

Safety Data

• Hazardous Substances Data: 77445-12-6(Hazardous Substances Data)

Upstream product

• 1994-40-7 1-(1-(4-fluorophenyl)ethylidene)-2-phenylhydrazine 
• 50-00-0 formaldehyd 
• 124-40-3 dimethyl amine 
• 782-17-2 2-(4-fluorophenyl)indole 

Relevant articles and documents

I2-induced cascade cyclization and dearomatization of indoles for the highly efficient synthesis of iodinated and vinylic spiroindolenines

The spiroindolenine framework is a privileged heterocyclic motif and is widely present in numerous indole alkaloids. Herein, we develop a metal-free and environmentally friendly approach for the intramolecular cascade cyclization and dearomatization of indole derivatives to selectively afford iodinated and vinylic spiroindolenines by a substrate-controlled strategy. Simple operation, mild conditions, and high yield make this strategy a green and attractive pathway to construct functionalizable spiroindolenine scaffolds, which could be converted into diverse useful spiroindolenine derivatives.