77471-41-1

Basic information

• Product Name: H-ALA-AMC
• Synonyms: H-ALA-AMC;L-ALANINE 4-METHYLCOUMARYL-7-AMIDE TOSYLATE;L-ALANINE-7-AMIDO-4-METHYLCOUMARIN;L-ALA-7-AMIDO-4-METHYLCOUMARIN;L-ALA-7-AMINO-4-METHYLCOUMARIN;L-ALA-AMC;L-ALANINE-4-METHYL-7-COUMARINYLAMIDE, FO R FLUORESCENCE;L-Alanine-4-methyl-7-coumarinylamide
• CAS NO: 77471-41-1
• Molecular Formula: C₁₃H₁₄N₂O₃
• Molecular Weight: 246.26
• Mol File: 77471-41-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 1.304
• Storage Temp.: -15°C
• CAS DataBase Reference: H-ALA-AMC(CAS DataBase Reference)
• NIST Chemistry Reference: H-ALA-AMC(77471-41-1)
• EPA Substance Registry System: H-ALA-AMC(77471-41-1)

Safety Data

• Safety Statements: 22-24/25
• Hazardous Substances Data: 77471-41-1(Hazardous Substances Data)

Usage

Chemical Properties

Off-white powder

Upstream product

• 26093-31-2 7-amino-4-methylcoumarin. 

Downstream Products

• 26093-31-2 7-amino-4-methylcoumarin. 
• 56-41-7 L-alanin 

Relevant articles and documents

Activity-Based Probe for Screening of High-Colibactin Producers from Clinical Samples

While high-colibactin-producing Escherichia coli is thought to be associated with colorectal oncogenesis, this study is complicated part due to an inability to isolate colibactin adequately. Here, we created fluorescent probes activated by ClbP, the colibactin-maturing peptidase, to identify high-colibactin-producing strains. Our probe served as a valuable clinical diagnostic tool that allowed simple high-throughput diagnostic screening of clinical samples. Furthermore, the probe also allowed identification of high-colibactin producers that would help advance our understanding of colibactin biosynthesis.