7749-51-1Relevant articles and documents
Heat shock protein 70 inhibitors. 1. 2,5′-thiodipyrimidine and 5-(phenylthio)pyrimidine acrylamides as irreversible binders to an allosteric site on heat shock protein 70
Kang, Yanlong,Taldone, Tony,Patel, Hardik J.,Patel, Pallav D.,Rodina, Anna,Gozman, Alexander,Maharaj, Ronnie,Clement, Cristina C.,Patel, Maulik R.,Brodsky, Jeffrey L.,Young, Jason C.,Chiosis, Gabriela
, p. 1188 - 1207 (2014/03/21)
Heat shock protein 70 (Hsp70) is an important emerging cancer target whose inhibition may affect multiple cancer-associated signaling pathways and, moreover, result in significant cancer cell apoptosis. Despite considerable interest from both academia and
Substituted pyrimidine derivatives
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Page/Page column 13, (2008/06/13)
The present invention relates to pyrimidine derivatives of the general formula I or salts thereof and their use.