7755-70-6

Basic information

• Product Name: 2-(Methylamino)benzaldehyde
• Synonyms: 2-(Methylamino)benzaldehyde
• CAS NO: 7755-70-6
• Molecular Formula: C₈H₉NO
• Molecular Weight: 135.1632
• Mol File: 7755-70-6.mol
• Article Data: 24

Chemical Properties

• Boiling Point: 260.7°Cat760mmHg
• Flash Point: 121.3°C
• Appearance: /
• Density: 1.121g/cm³
• Vapor Pressure: 0.0121mmHg at 25°C
• Refractive Index: 1.624
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• PKA: 2.96±0.10(Predicted)
• CAS DataBase Reference: 2-(Methylamino)benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Methylamino)benzaldehyde(7755-70-6)
• EPA Substance Registry System: 2-(Methylamino)benzaldehyde(7755-70-6)

Safety Data

• Hazardous Substances Data: 7755-70-6(Hazardous Substances Data)

Usage

General Description

2-(Methylamino)benzaldehyde is a chemical compound with the molecular formula C8H9NO. It is an aromatic aldehyde with a methylamino group attached to the benzene ring. 2-(Methylamino)benzaldehyde is commonly used as a building block in the synthesis of various pharmaceuticals and organic compounds. It is also used as a reagent in organic synthesis reactions. 2-(Methylamino)benzaldehyde is a versatile and important chemical with applications in the pharmaceutical and chemical industries.

InChI:InChI=1/C8H9NO/c1-9-8-5-3-2-4-7(8)6-10/h2-6,9H,1H3

Upstream product

• 271-58-9 anthranil 
• 77-78-1 dimethyl sulfate 
• 529-23-7 o-aminobenzaldehyde 
• 996-82-7 sodium diethylmalonate 
• 50609-25-1 1-methyl-2,1-benzisothiazolium iodide 
• 917-54-4 methyllithium 
• 119515-96-7 2-(Methyl-propoxy-amino)-benzaldehyde 
• 71492-76-7 N-allyl-N-methyl-2-bromoaniline 
• 119515-88-7 N-(2-bromophenyl)-N-methyl-O-propylhydroxylamine 
• 119515-87-6 o-bromo-N-methyl-N-allyloxyaniline 
• 3947-76-0 N-methylquinolinium iodide 
• 91-22-5 quinoline 
• 21979-19-1 1-methylquinolinium cation 
• 590-28-3 potassium cyanate 

Downstream Products

• 69905-99-3 2-methylaminobenzaldehyde oxime 
• 57091-71-1 N-(2-formylphenyl)-N-methylacetamide 
• 67984-94-5 1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid 
• 874635-68-4 1-methyl-2-phenyl-1,2-dihydroquinazolin-3-ium-3-olate 
• 2859-29-2 1-methyl-3-phenylquinolin-2(1H)-one 
• 1046820-38-5 N-methyl-N-geranyl-2-aminobenzaldehyde 
• 1046820-37-4 2-(methyl(3-methylbut-2-en-1-yl)amino)benzaldehyde 
• 841214-40-2 1-[[2-(methylamino)phenyl]methyl]-1H-indole 

Relevant articles and documents

Reduction of N-Nitrosaminoquinolinediones with LiAlH4 - An Easy Path to New Tricyclic Benzoxadiazocines

3-Butylaminoquinolinediones (1) react with NaNO2 in AcOH to give the corresponding N-nitrosoderivatives (2). The analogous reactions of 4-hydroxy-3-butylaminoquinolinediones (5), prepared by the reduction of 1 with NaBH4, produce the corresponding nitrosamines (4). The reduction of both 2 and 4 with Zn under different conditions was non-productive, but the reduction of both compounds with LiAlH4 at the oxo and lactame groups yielded impure products, generating new tricyclic benzoxadiazocines (9) by a reaction with HNCO. All compounds were characterized by IR, 1H-, and 13C-NMR (in some cases, 15N-NMR also) spectroscopy and EI and/or ESI mass spectrometry. The X-ray structure of compound 9g was determined.

Preparation method and application of new theophylline boric acid compound

The chemical formula of the compounds is shown in structural formulas (I) and (II). In-vitro antitumor activity screening results show that the compounds of the formula I and II have broad-spectrum anti-tumor activity and are used for human liver cancer (

Copper-Catalyzed (4+1) Cascade Annulation of Terminal Alkynes with 2-(Tosylmethyl)anilines: Synthesis of 2,3-Disubstituted Indoles

A novel strategy based on Cu-catalyzed (4+1) cascade annulation of terminal alkynes as one-carbon synthons with 2-(tosylmethyl)anilines has been developed for the expeditious synthesis of 2,3-disubstituted indoles, in which in situ generations of aza-o-quinone methides and alkynyl-copper(I) species are involved. This annulation provides an effective method for the assembly of synthetically and structurally interesting 2,3-disubstituted indoles.