77626-29-0

Basic information

• Product Name: 2(5H)-Oxazolone,4-[(1,1-dimethylethyl)amino]-5,5-dimethyl-(9CI)
• Synonyms: 2(5H)-Oxazolone,4-[(1,1-dimethylethyl)amino]-5,5-dimethyl-(9CI)
• CAS NO: 77626-29-0
• Molecular Formula: C₉H₁₆N₂O₂
• Molecular Weight: 184.23554
• Product Categories: N-BOC
• Mol File: 77626-29-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2(5H)-Oxazolone,4-[(1,1-dimethylethyl)amino]-5,5-dimethyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2(5H)-Oxazolone,4-[(1,1-dimethylethyl)amino]-5,5-dimethyl-(9CI)(77626-29-0)
• EPA Substance Registry System: 2(5H)-Oxazolone,4-[(1,1-dimethylethyl)amino]-5,5-dimethyl-(9CI)(77626-29-0)

Safety Data

• Hazardous Substances Data: 77626-29-0(Hazardous Substances Data)

Usage

Structure

A chemical compound containing an oxazolone ring, a tert-butylamino group, and two methyl groups.

Type

Derivative of oxazolone.

Usage

Building block in the synthesis of various organic compounds in pharmaceutical and chemical research.

Potential applications

Medicinal chemistry, specifically in the development of new drugs and treatments.

Properties

The specific properties and potential uses may vary depending on the context and intended application.

Upstream product

• 77609-26-8 [2-Bromo-1-tert-butylamino-2-methyl-prop-(E)-ylidene]-carbamic acid ethyl ester 
• 77609-28-0 (α-bromo-isobutyryl)-carbamic acid ethyl ester 

Downstream Products

• 695-53-4 dimethadione 

Relevant articles and documents

Chemistry of Hydrogen Isocyanide, 9. - Three-Component Cycloadditions with Cyano Complexes

A novel and obviously general reaction of the coordinated cyano ligand in - (M = Cr, W) is reported, viz. its high-yield one-step cycloaddition with a great variety of isocyanides and ketones resulting in carbenoid metal complexes of five-membered N,O heterocycles.The structure of the product 1a from -, tert-butyl isocyanide, and diethyl ketone has been elucidated by X-ray diffraction and found to contain a C-bound non-aromatic 4-aminooxazoline with an unprecedented ?-delocalization along the chain which is also evident from severe low-field shifts of the C-2 and C-4 signals in the 13C-NMR spectra.The heterocycles are cleaved off the metal by oxidative decomposition with KMnO4/Fe(NO3)3 to give the corresponding oxazolinones, e.g. 4, with a high potential for biological activity.The general validity of this reactivity pattern for metal cyanides is further demonstrated by the successful incorporation of cyanoiron(II) and -cobalt(III) species in these three-component cycloaddition reactions. - Key Words: Reactions at coordinated cyanide/ Cycloadditions, organometallic/ Carbenoid heterocycles/ Metal-ligand bond cleavage/ Oxazolinone syntheses