7770-45-8Relevant articles and documents
Switchable cascade C-H annulation to polycyclic pyryliums and pyridiniums: Discovering mitochondria-Targeting fluorescent probes
Chen, Xingyu,Yan, Lipeng,Liu, Yanhong,Yang, Yudong,You, Jingsong
, p. 15080 - 15083 (2020)
Disclosed herein is a counterion additive-switched rhodium-catalyzed cascade triple C-H annulation of 4-hydroxy-1-naphthaldehydes with alkynes, in which six chemical bonds are formed in one-pot. This reaction enables the rapid assembly of diverse polycycl
Acetal elimination reaction accompanied with regioselective ring opening of 1,4-bisacetal-1,4-epoxy-1,4-dihydronaphthalenes
Sawama, Yoshinari,Kawajiri, Takahiro,Yamamoto, Yuta,Shishido, Yuko,Goto, Ryota,Sajiki, Hironao
, p. 126 - 133 (2019/06/24)
– 1,4-Epoxy-1,4-dihydronaphthalenes are useful precursors to synthesize 1-naphthols by an acid-catalyzed ring opening of their 1,4-epoxy moieties. 1-Acetal-substituted 1,4-epoxy-1,4-dihydronaphthalene was also converted to 1-naphthol via the unique iron-catalyzed ring opening of the 1,4-epoxy moiety followed by the elimination of the acetal moiety. The present method could be applied to the regioselective syntheses of highly-functionalized 4-formyl-1-naphthols from the unsymmetrical 1,4-bisacetal-substituted 1,4-epoxy-1,4-dihydronaphthalenes.
Asymmetric dearomative spirolactonization of naphthols using λ3-iodanes under chiral phase-transfer catalysis
Antien, Kevin,Viault, Guillaume,Pouységu, Laurent,Peixoto, Philippe A.,Quideau, Stéphane
supporting information, p. 3684 - 3690 (2017/06/13)
The asymmetric phase-transfer catalytic effect of chiral Cinchona alkaloid-derived quaternary ammonium salts was investigated in the context of the λ3-iodane-mediated dearomative spirolactonization of naphthols. The scope and limitations of this methodology were evaluated using various substrates, which were converted into spirolactones in good yields and with enantiomeric excesses up to 58%.