7784-67-0

Basic information

• Product Name: 2-methoxy-4-prop-1-enylphenetole
• Synonyms: 2-methoxy-4-prop-1-enylphenetole;Ethyl-iso-eugenol;Benzene, 1-ethoxy-2-methoxy-4-(1-propenyl)-;ISOEUGENYLETHYLETHER;Ethyl isoeugenyl ether;2-Methoxy-4-(1-propenyl)phenylethyl ether;Benzene, 1-ethoxy-2-Methoxy-4-(1-propen-1-yl)-;isoeugenyl ether ether
• CAS NO: 7784-67-0
• Molecular Formula: C₁₂H₁₆O₂
• Molecular Weight: 192.25424
• EINECS: 232-072-6
• Mol File: 7784-67-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 288oC at 760 mmHg
• Flash Point: 109.7oC
• Appearance: white crystalline powder
• Density: 0.986g/cm3
• Vapor Pressure: 0.00415mmHg at 25°C
• Refractive Index: 1.529
• CAS DataBase Reference: 2-methoxy-4-prop-1-enylphenetole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxy-4-prop-1-enylphenetole(7784-67-0)
• EPA Substance Registry System: 2-methoxy-4-prop-1-enylphenetole(7784-67-0)

Safety Data

• Hazardous Substances Data: 7784-67-0(Hazardous Substances Data)

Usage

Description

Isoeugenyl ethyl ether has an odor similar to isoeugenol. Prepared from isoeugenol by boiling with ethyl p-toluenesulfonate.

Chemical Properties

Isoeugenyl ethyl ether has an odor similar to isoeugenol.

Uses

Ethylisoeugenol is a prenylated dehydrozingerone analog, a potent potential chemopreventive agent for cancer.

Preparation

From isoeugenol by boiling with ethyl p-toluenesulfonate.

Synthesis Reference(s)

Synthetic Communications, 20, p. 345, 1990 DOI: 10.1080/00397919008052774

InChI:InChI=1/C12H16O2/c1-4-6-10-7-8-11(14-5-2)12(9-10)13-3/h4,6-9H,5H2,1-3H3/b6-4+

Upstream product

• 64-67-5 diethyl sulfate 
• 97-54-1 2-methoxy-4-propenylphenol 
• 74368-00-6 4-allyl-1-ethoxy-2-methoxybenzene 
• 75-03-6 ethyl iodide 
• 97-53-0 4-allylguaiacol 
• 105-58-8 Diethyl carbonate 

Downstream Products

• 3535-30-6 4-ethoxy-3-methoxybenzoic acid 
• 2067-94-9 1-ethoxy-4-(1,2-dibromo-propyl)-2-methoxy-benzene 
• 102898-11-3 5-ethoxy-3-(4-ethoxy-3-methoxy-phenyl)-1-ethyl-6-methoxy-2-methyl-indan 
• 110050-99-2 2,6-diethoxy-3,7-dimethoxy-anthraquinone 
• 120-25-2 4-ethoxy-3-methoxybenzaldehyde 
• 102898-11-3 (+/-)-5-ethoxy-3t-(4-ethoxy-3-methoxy-phenyl)-1r-ethyl-6-methoxy-2c-methyl-indan 
• 97-54-1 2-methoxy-4-propenylphenol 
• 94-86-0 2-ethoxy-5-propenylphenol 
• 833-67-0 1-(4-ethoxy-3-methoxy-phenyl)-propan-1-one 

Relevant articles and documents

Synthetic method for ethyl isoeugenol

The invention discloses a synthetic method for ethyl isoeugenol, and belongs to the technical field of fine organic chemical synthesis. The synthetic method includes the steps that eugenol and DEC serve as raw materials, the DEC is added stepwise and dropwise, under catalysis of solid alkali and a phase transfer catalyst, and through a reaction distillation technology, the ethyl isoeugenol is synthesized with the one-step method. According to the synthetic method for the ethyl isoeugenol, the relative-environmental-protection chemical reagent DEC is used for replacing high-toxicity and high-corrosivity diethyl sulfate used at present to serve as an ethylation reagent, and in stepwise and dropwise modes, a catalytic system of the solid alkali and the phase transfer catalyst is selected, andthe ethyl isoeugenol is synthesized with the one-step method; the eugenol-isomerization-and-ethylation two-step-reacting synthetic process needed at present and a one-time adding mode of DEC are changed. The synthetic method is a relative-environmental-protection synthetic route, the synthetic route is short, reaction time is short, the product yield is high, energy is saved, consumption is reduced, and the synthetic method for the ethyl isoeugenol has good industrial application prospects.

Potassium Fluoride on Alumina - a Versatile Reagent for Isomerisation of Olefins

Olefins undergo smooth isomerization to the thermodynamically more stable form on treatment with potassium fluoride coated on alumina.