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77887-07-1

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77887-07-1 Usage

General Description

Thymidine 3'-acetate=5'-[bis(2,2-dimethyl-1-aziridinyl)phosphinic acid] is a chemical compound with the formula C13H20N3O7P. It is a derivative of thymidine, a nucleoside found in DNA, and contains an acetate and phosphinic acid group. The presence of the phosphinic acid group makes it a potential antiviral and anticancer agent, as it can inhibit the synthesis of DNA and RNA. Additionally, the aziridinyl groups in the molecule have the potential to act as alkylating agents, forming covalent bonds with DNA and causing cellular damage to cancer cells. Thymidine 3'-acetate=5'-[bis(2,2-dimethyl-1-aziridinyl)phosphinic acid] has potential applications in chemotherapy and antiviral therapy, but further research is needed to fully understand its mechanisms and potential therapeutic uses.

Check Digit Verification of cas no

The CAS Registry Mumber 77887-07-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,8,8 and 7 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 77887-07:
(7*7)+(6*7)+(5*8)+(4*8)+(3*7)+(2*0)+(1*7)=191
191 % 10 = 1
So 77887-07-1 is a valid CAS Registry Number.
InChI:InChI=1/C20H31N4O7P/c1-12-8-22(18(27)21-17(12)26)16-7-14(30-13(2)25)15(31-16)9-29-32(28,23-10-19(23,3)4)24-11-20(24,5)6/h8,14-16H,7,9-11H2,1-6H3,(H,21,26,27)

77887-07-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name [2-[bis(2,2-dimethylaziridin-1-yl)phosphoryloxymethyl]-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl] acetate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:77887-07-1 SDS

77887-07-1Downstream Products

77887-07-1Relevant articles and documents

Synthesis of 5'-thymidinyl bis(1-aziridinyl)phosphinates as antineoplastic agents

Hsiao,Bardos

, p. 887 - 889 (2007/10/02)

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