7789-45-9 Usage
Description
Cupric bromide, also known as copper(II) bromide, is an inorganic compound derived from the reaction between copper oxide and hydrobromic acid. It is an odorless black solid that sinks and mixes with water, and it can be used in various applications due to its unique chemical properties.
Uses
Used in Organic Synthesis:
Cupric bromide is used as a catalyst in organic reactions, particularly in cross-coupling and Sonogashira coupling reactions. It also serves as a brominating agent in organic synthesis, facilitating the formation of new chemical bonds.
Used in Photography:
In the photography industry, cupric bromide is used as an intensifier, enhancing the development of photographic images and improving their quality.
Used in Wood Preservation:
Cupric bromide is employed as a wood preservative, protecting wood from decay and damage caused by fungi, insects, and other environmental factors.
Used in Batteries:
Cupric bromide finds application in solid-electrolyte batteries, contributing to their efficient energy storage and discharge capabilities.
Used in Polymerization:
It is used in living radical polymerization, a process that allows for the controlled formation of polymers with specific properties and structures.
Used in Dermatology:
The cupric bromide laser is an important technology in dermatology, used for the treatment of pigmented lesions and vascular lesions.
Used in Humidity Indication:
Cupric bromide can be used as a humidity indicator, helping to monitor and control moisture levels in various environments.
Used in Stabilization:
It is used as a stabilizer for acetylated polyformaldehyde, a type of plastic material.
Used in Pharmaceutical Synthesis:
Cupric bromide is used in the coupling of o-iodophenols and aryl acetylenes, avoiding the need for palladium catalysts. It is also employed in the preparation of NK1/NK2 receptor antagonists, which are used in the regulation of tachykinin.
Used in Enantioselective Synthesis:
Cupric bromide acts as a Lewis acid in the enantioselective addition of alkynes, a process that is crucial for the synthesis of chiral compounds with specific configurations.
Used in Controlled Polymerization:
When complexed by three molecules of pyridine, cupric bromide serves as an initiator for the controlled polymerization of styrene, methyl acrylate, and methyl methacrylate.
Used in Reductive Homocoupling:
Cupric bromide, in the presence of CuBr/LiOCH3 in methanol, is used for the reductive homocoupling of α-bromo-α-chlorocarboxylates to dimethyl α,α'-dichlorosuccinate derivatives.
Chemical Properties:
Cupric bromide (CuBr2) is a black, deliquescent, monoclinic, crystalline material with a molecular weight of 223.36 and a melting point of 498°C. It is very soluble in water and soluble in alcohol and acetone. At temperatures below 29°C, it forms a green tetrahydrate.
Preparation
Copper(II) bromide is most easily prepared by neutralization of copper(II) oxide, carbonate, or hydroxide with hydrobromic acid. It can also be produced by oxidation of copper metal with bromine water or by reaction of bromine solutions in alcohol with copper powder.
References
Shen, Youqing, Shiping Zhu, and Robert Pelton. Macromolecules 34.10 (2001): 3182-3185.
Rothfleisch, Jeremy E., et al. Dermatologic clinics 20.1 (2002): 1- 18.
Huang, Jianhui, Simon JF Macdonald, and Joseph PA Harrity. Chemical Communications 4 (2009): 436-438.
Besselièvre, Fran?ois, and Sandrine Piguel. Angewandte Chemie International Edition 48.50 (2009): 9553-9556.
Reactivity Profile
Acidic inorganic salts, such as Cupric bromide, are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.
Health Hazard
Inhalation of dust causes irritation of throat and lungs. Ingestion of large amounts causes violent vomiting and purging, intense pain, collapse, coma, convulsions, and paralysis. Contact with solutions causes eye irritation; contact with solid causes severe eye surface injury and skin irritation.
Fire Hazard
Special Hazards of Combustion Products: Irritating hydrogen bromide gas may form in fire.
Flammability and Explosibility
Notclassified
Purification Methods
Crystallise it twice by dissolving it in water (140mL/g), filtering to remove any Cu2Br2, and concentrating under vacuum at 30o until crystals appear. The cupric bromide is then allowed to crystallise by leaving the solution in a vacuum desiccator containing P2O5 [Hope et al. J Chem Soc 5226 1960, Glemser & Sauer in Handbook of Preparative Inorganic Chemistry (Ed. Brauer) Academic Press Vol II p 1009 1965].
Check Digit Verification of cas no
The CAS Registry Mumber 7789-45-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,7,8 and 9 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 7789-45:
(6*7)+(5*7)+(4*8)+(3*9)+(2*4)+(1*5)=149
149 % 10 = 9
So 7789-45-9 is a valid CAS Registry Number.
InChI:InChI=1/2BrH.Cu/h2*1H;/q;;+2/p-2/rBr2Cu/c1-3-2
7789-45-9Relevant articles and documents
Electronic and vibrational structure of copper dibromide
Lorenz, Martin,Bondybey, Vladimir E.
, p. 5429 - 5436 (2002)
Absorption and laser-induced fluorescence spectra of copper dibromide in a solid neon matrix are reported. Similar to those for copper dichloride, electronic transitions between the low-lying so-called ligand field states states are forbidden by the u?g rule, appear as a result of vibronic Herzberg-Teller coupling. The observed transition energies are in good agreement with the adiabatic state energies derived from a recent gas-phase photodetachment study by Wang and co-workers. The matrix study with its much higher resolution yields detailed information about the copper halide electronic states and their vibrational structures.
Bateman, W. E.,Conrad, D. B.
, p. 2553 - 2560 (1915)
Copper (II) halide complexes with NNO tridentate ligand as chromotropic probes; synthesis, structural characterization and spectroscopic properties
Bouwman, Elisabeth,Golchoubian, Hamid,Shirvan, Atie,Siegler, Maxime A.
, (2021)
This study reports chromotropism of two newly synthesized copper(II) complexes of formula [CuLCl2] and [CuLBr2]?MeOH where L = N-(2-pyridylmethyl)-1-hydroxypropylamine. The structure of the complexes was investigated by infrared spectroscopy, electronic absorption spectroscopy, elemental analysis, molar conductance measurements, and thermal analysis. Single Crystal X-ray structure determination reveals both complexes to adopt a distorted square-pyramidal geometry. Their chromotropic properties were investigated using electronic absorption spectroscopy. The complexes are solvatochromic in solvents with different polarities. The aqueous solutions of the complexes exhibit a variety of colors in the pH range of 1.8 to 11.4 showing that the compounds are halochromic. The complexes are also thermochromic and show reversible color changes in different temperatures in dimethyl sulfoxide solutions. The solution study reveals that the observed chromotropism originates from structural changes of the complexes in different conditions.
Microwave-assisted carbohydrohalogenation of first-row transition-metal oxides (M = V, Cr, Mn, Fe, Co, Ni, Cu) with the formation of element halides
Berger, Matthias,Neumeyer, Felix,Auner, Norbert
supporting information, p. 11691 - 11693 (2013/11/19)
The anhydrous forms of first-row transition-metal chlorides and bromides ranging from vanadium to copper were synthesized in a one-step reaction using the relatively inexpensive element oxides, carbon sources, and halogen halides as starting materials. The reactions were carried out in a microwave oven to give quantitative yields within short reaction times.