7791-13-1 Usage
Chemical Description
Cobalt chloride hexahydrate is a cobalt salt used in the synthesis of cobaloximes.
Description
Cobalt chloride hexahydrate, also known as CoCl2·6H2O, is a crystalline compound that is highly soluble in water. It is a versatile chemical with a variety of applications across different industries due to its unique properties.
Uses
Used in Hygrometers:
Cobalt chloride hexahydrate is used as a humidity indicator in hygrometers for its ability to change color based on the moisture content in the air.
Used in Grinding:
It serves as a temperature indicator in grinding processes, helping to monitor and control the temperature during the operation.
Used in Brewing Industry:
Cobalt chloride hexahydrate is used as a foam stabilizer in beer, contributing to the formation and stability of the foam head.
Used in Invisible Ink:
Cobalt chloride hexahydrate is utilized in the creation of invisible ink, which becomes visible under specific conditions.
Used in Glass Painting:
It is employed for painting on glass, providing a unique aesthetic effect.
Used in Electroplating:
Cobalt chloride hexahydrate is used in electroplating processes to achieve a decorative or functional coating on various substrates.
Used in Grignard Reactions:
It acts as a catalyst in Grignard reactions, promoting the coupling of an organic halide with other compounds.
Used in Synthesis of Cobalt Salts:
Cobalt chloride hexahydrate is used to prepare several other cobalt salts, which have their own specific applications.
Used in Synthetic Vitamin B12 Production:
Cobalt chloride hexahydrate is employed in the manufacture of synthetic vitamin B12, an essential nutrient for the human body.
Used in Chemical Synthesis:
It has been found to be an efficient catalyst for the one-pot synthesis of biscoumarin derivatives through a combination of aromatic aldehydes and 4-hydroxycoumarin in aqueous media at 70°C.
Used in Biological Research:
Cobalt chloride hexahydrate can be used as an inducer of HIF-1 production, which is utilized to study apoptotic effects in HepG2 cells.
Used as APHA Color Standard:
Cobalt chloride hexahydrate is also used as an APHA color standard, which is a measure of color intensity in water samples.
Preparation
Cobalt(II) chloride is prepared by the action of cobalt metal or its oxide, hydroxide, or carbonate with hydrochloric acid:
Co(OH)2 + 2HCl → CoCl2 + 2H2O
The solution on concentration and cooling forms crystals of hexahydrate which on heating with SOCl2 dehydrates to anhydrous cobalt(II) chloride. Alternatively, the hexahydrate may be converted to anhydrous CoCl2 by dehydration in a stream of hydrogen chloride and dried in vacuum at 100–150°C.
The anhydrous compound also may be obtained by passing chlorine over cobalt powder.
Reactions
Cobalt(II) chloride undergoes many double decomposition reactions in aqueous solution to produce precipitates of insoluble cobalt salts. For example, heating its solution with sodium carbonate yields cobalt(II) carbonate:
CoCl2 + Na2CO3 CoCO3 + 2NaCl
Reaction with alkali hydroxide produces cobalt(II) hydroxide:
CoCl2 + 2NaOH → Co(OH)2 + 2NaCl
Reaction with ammonium hydrogen phosphate yields cobalt(II) phosphate:
3CoCl2 + 2(NH4)2HPO4 → Co3(PO4)2 +4NH4Cl + 2HCl
While cobalt(II) fluoride is the product of the reaction of anhydrous cobalt(II) chloride with hydrofluoric acid, cobalt(III) fluoride is obtained from fluorination of an aqueous solution of cobalt(II) chloride.
Addition of potassium nitrite, KNO2 to a solution of cobalt(II) chloride yields yellow crystalline potassium hexanitrocobaltate(III), K3Co(NO2)6.
Toxicity
The compound is toxic at high doses. Symptoms include chest pain, cutaneous flushing, nausea, vomiting, nerve deafness, and congestive heart failure. The systemic effects in humans from ingestion include anorexia, increased thyroid size, and weight loss (Lewis (Sr.), R. J. 1996. Sax’s Dangerous Properties of Industrial Materials, 9th ed. New York: Van Nostrand Reinhold). Ingestion of a large amount (30–50 g) could be fatal to children.
Structure and conformation
The hexahydrate COCl2.6H2O forms monoclinic crystals in which each cobalt atom is surrounded by four water molecules at the corners of a distorted square (Co-H20 = .12) and by two chlorine atoms (Co-Cl = 2.43) to form a distorted octahedron.The other two water molecules are not bonded directly to cobalt. In the monoclinic dihydrate CoCl2.2H2O, the octahedral symmetry around the cobalt atom is maintained by the sharing of chlorine atoms between two cobalt atoms. In the flattened octahedral structuress there are two Co-Cl distances of 2-450, two of 2.478 and two Co-H2O distances of 2.040.
Check Digit Verification of cas no
The CAS Registry Mumber 7791-13-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,7,9 and 1 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 7791-13:
(6*7)+(5*7)+(4*9)+(3*1)+(2*1)+(1*3)=121
121 % 10 = 1
So 7791-13-1 is a valid CAS Registry Number.
InChI:InChI=1/ClH.Co.6H2O/h1H;;6*1H2/q;+2;;;;;;/p-1
