781649-84-1

Basic information

• Product Name: 2-Oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridine dihydrochloride
• Synonyms: 2-Oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridine dihydrochloride;1-(Piperidin-4-yl)-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one dihydrochloride;1,3-Dihydro-1-(4-piperidinyl)-2H-imidazo[4,5-b]pyridin-2-one hydrochloride;1-Piperidin-4-yl-1,3-dihydroimidazo[4,5-b]pyridin-2-one dihydrochloride;2-oxo-1-(4-piperidinyl)-2,3-;1-(Piperidin-4-yl)-1H-iMidazo[4,5-b]pyridin-2(3H)-one (Hydrochloride);1-(Piperidin-4-yl)-1H-iMidazo[4,5-b]pyridin-2(3H)-one dihydrochloride;1-(Piperidin-4-yl)-1H,2H,3H-imidazo-[4,5-b]pyridin-2-one dihydrochloride
• CAS NO: 781649-84-1
• Molecular Formula: C11H16Cl2N4O
• Molecular Weight: 291.17694
• EINECS: 616-591-9
• Product Categories: yy
• Mol File: 781649-84-1.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 450.5°C at 760 mmHg
• Flash Point: 226.3°C
• Appearance: /
• Vapor Pressure: 1.61E-08mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 2-Oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridine dihydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridine dihydrochloride(781649-84-1)
• EPA Substance Registry System: 2-Oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridine dihydrochloride(781649-84-1)

Safety Data

• Hazardous Substances Data: 781649-84-1(Hazardous Substances Data)

Usage

Description

2-Oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridine dihydrochloride is a chemical compound that serves as an intermediate in the synthesis of pharmaceuticals, specifically in the preparation of Telcagepant (MK-0974), a calcitonin gene-related peptide receptor antagonist used for treating migraine headaches.

Uses

Used in Pharmaceutical Industry:
2-Oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridine dihydrochloride is used as a key intermediate in the synthesis of Telcagepant (MK-0974), a calcitonin gene-related peptide receptor antagonist. 2-Oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridine dihydrochloride plays a crucial role in the development of medications for the treatment of migraine headaches, offering a targeted approach to alleviate the symptoms and reduce the frequency of these debilitating episodes.

InChI:InChI=1/C11H14N4O.2ClH/c16-11-14-10-9(2-1-5-13-10)15(11)8-3-6-12-7-4-8;;/h1-2,5,8,12H,3-4,6-7H2,(H,13,14,16);2*1H