782-87-6

Basic information

• Product Name: 3-[BENZYL-(2-CYANO-ETHYL)-AMINO]-PROPIONITRILE
• Synonyms: 3-[BENZYL-(2-CYANO-ETHYL)-AMINO]-PROPIONITRILE;3,3'-[(phenylmethyl)imino]bisPropanenitrile
• CAS NO: 782-87-6
• Molecular Formula: C₁₃H₁₅N₃
• Molecular Weight: 213.28
• Mol File: 782-87-6.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 429.3 °C at 760 mmHg
• Flash Point: 195.3 °C
• Appearance: /
• Density: 1.072 g/cm³
• CAS DataBase Reference: 3-[BENZYL-(2-CYANO-ETHYL)-AMINO]-PROPIONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[BENZYL-(2-CYANO-ETHYL)-AMINO]-PROPIONITRILE(782-87-6)
• EPA Substance Registry System: 3-[BENZYL-(2-CYANO-ETHYL)-AMINO]-PROPIONITRILE(782-87-6)

Safety Data

• Hazardous Substances Data: 782-87-6(Hazardous Substances Data)

Usage

Description

3-[BENZYL-(2-CYANO-ETHYL)-AMINO]-PROPIONITRILE, with the molecular formula C15H16N2, is a propionitrile derivative that features a benzyl group and a 2-cyano-ethyl-amino group. This chemical compound is recognized for its versatility and potential applications across various fields, making it a valuable building block in the chemical industry.
Used in Pharmaceutical Research:
3-[BENZYL-(2-CYANO-ETHYL)-AMINO]-PROPIONITRILE is used as a starting material for the preparation of various drugs and biologically active molecules. Its unique structure allows for the development of new pharmaceutical compounds with potential therapeutic applications.
Used in Organic Synthesis:
In the realm of organic synthesis, 3-[BENZYL-(2-CYANO-ETHYL)-AMINO]-PROPIONITRILE serves as a key intermediate, facilitating the creation of a wide range of chemical products through its reactive functional groups.
Used in Chemical Intermediates Production:
3-[BENZYL-(2-CYANO-ETHYL)-AMINO]-PROPIONITRILE is utilized in the production of dyes, pigments, and other chemical intermediates, contributing to the coloration and enhancement of various products in different industries.
Used in Dye and Pigment Industries:
3-[BENZYL-(2-CYANO-ETHYL)-AMINO]-PROPIONITRILE is used as a chemical intermediate for the development of dyes and pigments, providing a foundation for the creation of vibrant colors and shades in textiles, paints, and other applications.

Upstream product

• 111-94-4 3,3'-Iminodipropionitrile 
• 100-44-7 benzyl chloride 
• 620-05-3 iodomethylbenzene 
• 107-13-1 acrylonitrile 
• 100-46-9 benzylamine 
• 100-39-0 benzyl bromide 
• 706-03-6 3-(benzylamino)propionitrile 

Downstream Products

• 1555-71-1 N1-(3-amino-propyl)-N1-benzyl-propane-1,3-diamine 
• 66128-33-4 N,N-bis(3-(N,N-bis(3-aminopropyl)amino)propyl)benzylamine 
• 66128-32-3 3-[[3-(benzyl-{3-[bis-(2-cyano-ethyl)-amino]-propyl}-amino)-propyl]-(2-cyano-ethyl)-amino]-propionitrile 
• 14247-04-2 4-amino-1-benzyl-1.2.5.6-tetrahydropyridine-3-carbonitrile 
• 881693-44-3 N,N'-bis(p-bromobenzenesulfonyl)bis(3-aminopropyl)benzylamine 
• 881693-48-7 N,N'-bis(m-nitrobenzenesulfonyl)bis(3-aminopropyl)benzylamine 
• 881693-47-6 N,N'-bis(o-nitrobenzenesulfonyl)bis(3-aminopropyl)benzylamine 
• 881693-46-5 N,N'-bis(p-butoxymethylbenzenesulfonyl)bis(3-aminopropyl)benzylamine 
• 47771-56-2 N⁴-benzyl-N¹,N⁷-ditosyl-4-aza-1,7-heptanediamine 
• 47741-42-4 N,N'-bis(benzenesulfonyl)bis(3-aminopropyl)benzylamine 
• 14205-01-7 N,N'-bis(p-nitrobenzenesulfonyl)bis(3-aminopropyl)benzylamine 
• 182316-34-3 9-benzyl-3-methylene-1,5-bis(benzenesulfonyl)-1,5,9-triazacyclododecane 
• 471867-02-4 9-Benzyl-1,5-bis-(4-bromo-benzenesulfonyl)-3-methylene-1,5,9-triaza-cyclododecane 
• 182316-06-9 3-methylene-1,5-bis(4-methylbenzenesulfonyl)-1,5,9-triazacyclododecane 

Relevant articles and documents

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Cultivation of a Cu/HMPC catalyst from a hyperaccumulating mustard plant for highly efficient and selective coupling reactions under mild conditions

Cu-containing activated carbon (eco-catalyst, Cu/HMPC, where 'C' defines 'carbon') was derived from a metal-hyperaccumulating mustard plant (HMP) by a simple chemical activation method. Transmission electron microscopy/selected area diffraction (HRTEM/SAED) results revealed that the Cu/HMPC has mainly three types of morphology [sheet-like morphology (2D), hollow-spheres (3D) and needle-like structures (1D)] which are interconnected. HRTEM-SAED, Raman and X-ray photoelectron spectroscopy (XPS) results confirmed the existence of Cu oxide species in Cu/HMPC. Content of Cu in Cu/HMPC was determined to be 1.03 wt%. The quality of graphitization in Cu/HMPC was discussed by using Raman and XRD results. The BET surface area of Cu/HMPC was determined to be 620.8 m2 g-1. The Cu/HMPC actively transformed a wide range of amines to imines under very mild reaction conditions. The catalyst Cu/HMPC gave products in excellent yields (98-61%) with very high TON/TOF values (1512/339-833/35 h-1). To the best of our knowledge, this is the most efficient Cu-based heterogeneous eco-catalyst for the synthesis of imines among those reported to date. The Cu can be recovered from used Cu/HMPC by a simple HCl treatment. Versatility, heterogeneity and reusability of Cu/HMPC were tested. A possible mechanism has been proposed.

Unsymmetrical cyclotriazadisulfonamide (CADA) compounds as human CD4 receptor down-modulating agents

Cyclotriazadisulfonamide (CADA) inhibits HIV at submicromolar levels by specifically down-modulating cell-surface and intracellular CD4. The specific biomolecular target of CADA compounds is unknown, but previous studies led to an unsymmetrical binding model. To test this model, methods were developed for effective synthesis of diverse, unsymmetrical CADA compounds. A total of 13 new, unsymmetrical target compounds were synthesized, as well as one symmetrical analogue. The new compounds display a wide range of potency for CD4 down-modulation in CHO-CD4-YFP cells. VGD020 (IC50 = 46 nM) is the most potent CADA compound discovered to date, and VGD029 (IC50 = 730 nM) is the most potent fluorescent analogue. Structure-activity relationships are analyzed from the standpoint of additive or nonadditive energy effects of different substituents. They appear to be consistent with the zipper-type mechanism in which entropy costs are reduced for additional stabilizing interactions between the small molecule and its protein target.