783321-80-2 Usage
Description
2,5-DICHLOROANILINE-3,4,6-D3 is an isotopically labeled research compound with the chemical formula C6D3Cl2NH2. It is a derivative of 2,5-dichloraniline, where three hydrogen atoms are replaced with deuterium atoms, making it a valuable tool for scientific research and analysis.
Uses
Used in Chemical Research:
2,5-DICHLOROANILINE-3,4,6-D3 is used as a research compound for studying chemical reactions and mechanisms. The presence of deuterium atoms allows for the investigation of reaction kinetics, isotope effects, and the behavior of molecules in various chemical processes.
Used in Analytical Chemistry:
In analytical chemistry, 2,5-DICHLOROANILINE-3,4,6-D3 serves as an internal standard or a reference compound for accurate quantification and identification of related compounds in complex mixtures. Its isotopically labeled nature provides a distinct signature, facilitating precise measurements and comparisons.
Used in Pharmaceutical Development:
2,5-DICHLOROANILINE-3,4,6-D3 can be utilized in the development of pharmaceutical drugs, particularly as a starting material or an intermediate in the synthesis of novel therapeutic agents. Its unique properties may contribute to the discovery of new drugs with improved efficacy and selectivity.
Used in Environmental Studies:
This isotopically labeled compound can also be employed in environmental studies to trace the fate and transport of related pollutants or contaminants in various ecosystems. The incorporation of deuterium atoms enables the differentiation between natural and anthropogenic sources, providing valuable insights into environmental processes and pollution control strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 783321-80-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,8,3,3,2 and 1 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 783321-80:
(8*7)+(7*8)+(6*3)+(5*3)+(4*2)+(3*1)+(2*8)+(1*0)=172
172 % 10 = 2
So 783321-80-2 is a valid CAS Registry Number.
783321-80-2Relevant articles and documents
Synthesis of chlorinated and non-chlorinated biphenyl-2,3- and 3,4-catechols and their [2H3]-isotopomers
Lin, Po-Hsiung,Sangaiah,Ranasinghe, Asoka,Ball, Louise M.,Swenberg, James A.,Gold, Avram
, p. 2624 - 2629 (2007/10/03)
A synthetic scheme is described for chlorinated biphenyl-2,3- and 3,4-catechols to be used as standards for structural assignment of metabolites and protein adducts of 2,2′,5,5′-tetrachlorobiphenyl in which both rings retain chlorine substituents. The scheme has general applicability to the synthesis of chlorinated biphenyl catechols. Dimethyl catechol ethers are coupled to dichloroaniline via the Cadogan reaction to give a library of isomers, followed by demethylation of the ethers with BBr3 to yield the target catechols. Separation of pure isomers is accomplished by TLC or HPLC prior to or following demethylation, depending on the isomer mixture. [ 2H3]-Isotopomers are generated using 2,5-dichloroaniline- d3 as the starting arylamine in the coupling reaction. The dichloroaniline-d3 hydrochloride is obtained as the sole product from nitration of p-dichlorobenzene-d4 followed by Pd/C-catalyzed hydrogenation under strongly acidic conditions. This hydrogenation procedure provides a simple and convenient approach to selective reduction of aryl nitro groups in the presence of halogen ring substituents.
