78430-91-8 Usage
Description
1-[(4-ethenylphenyl)Methyl]-1H-Imidazole, commonly known as clotrimazole, is an antifungal medication that is widely used to treat yeast infections affecting the skin, mouth, and vagina. It functions by inhibiting the growth of the fungal cell membrane, ultimately leading to the death of the fungus. Clotrimazole is available in various forms, including creams, lotions, powders, and lozenges, which facilitates its application to the affected areas. It is generally well-tolerated with minimal side effects, although some individuals may experience mild irritation or allergic reactions.
Uses
Used in Pharmaceutical Industry:
1-[(4-ethenylphenyl)Methyl]-1H-Imidazole is used as an antifungal agent for treating yeast infections such as candidiasis, which can affect the skin, mouth, and vagina. Its application reason is due to its ability to inhibit the growth of the fungal cell membrane, resulting in the death of the fungus and providing relief for the infected individual.
Used in Topical Medications:
In the form of creams and lotions, 1-[(4-ethenylphenyl)Methyl]-1H-Imidazole is used as a topical treatment for skin infections caused by yeasts. The application reason is its effectiveness in targeting the fungal cell membrane and reducing inflammation and discomfort associated with the infection.
Used in Oral Health:
1-[(4-ethenylphenyl)Methyl]-1H-Imidazole is used as an oral antifungal agent in the form of lozenges for treating oral thrush and other yeast infections in the mouth. The application reason is its ability to directly target the fungus in the oral cavity, alleviating symptoms and promoting healing.
Used in Gynecological Treatments:
In the form of vaginal creams or suppositories, 1-[(4-ethenylphenyl)Methyl]-1H-Imidazole is used as a treatment for vaginal yeast infections. The application reason is its targeted action on the fungal cell membrane, which helps to eliminate the infection and restore a healthy vaginal environment.
Check Digit Verification of cas no
The CAS Registry Mumber 78430-91-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,4,3 and 0 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 78430-91:
(7*7)+(6*8)+(5*4)+(4*3)+(3*0)+(2*9)+(1*1)=148
148 % 10 = 8
So 78430-91-8 is a valid CAS Registry Number.
78430-91-8Relevant articles and documents
Water swelling, brine soluble imidazole based zwitterionic polymers-synthesis and study of reversible UCST behaviour and gel-sol transitions
Vasantha, Vivek Arjunan,Jana, Satyasankar,Parthiban, Anbanandam,Vancso, Julius G.
, p. 46 - 48 (2013)
New vinylbenzene substituted imidazole based zwitterionic polymers with unique characteristics like swelling in water and solubility in concentrated brine solution in which they exhibited a reversible upper critical solution temperature (UCST) and gel-sol transitions are reported herein.
Rose Bengal Immobilized on Supported Ionic-Liquid-like Phases: An Efficient Photocatalyst for Batch and Flow Processes
Valverde, David,Porcar, Raul,Izquierdo, Diana,Burguete, M. Isabel,Garcia-Verdugo, Eduardo,Luis, Santiago V.
, p. 3996 - 4004 (2019/08/01)
The catalytic activity of Rose Bengal (RB) immobilized on supported ionic liquid (IL)-like phases was evaluated as a polymer-supported photocatalyst. In these systems, the polymer was designed to play a pivotal role. The polymeric backbone adequately modi
1,3-Dipolar cycloaddition reaction of aryl nitrile oxides with alkenes using imidazole and pyridine containing reusable polymeric base catalysts
Korgavkar, Nilesh N.,Samant, Shriniwas D.
supporting information, p. 387 - 394 (2018/02/06)
Cross-linked poly-1-(4-vinylbenzyl)imidazole and cross-linked poly-4-vinylpyridine have been prepared from respective vinyl monomers using different quantities of divinylbenzene as a cross-linker by radical polymerization. The polymeric bases were charact
N-heterocyclic carbene coordinated heterogeneous Pd nanoparticles as catalysts for suzuki-miyaura coupling
Min, Hyemin,Miyamura, Hiroyuki,Kobayashi, Shu
supporting information, p. 837 - 839 (2016/07/16)
Palladium nanoparticle (Pd NP) catalysts immobilized in a polymer with an N-heterocyclic carbene (NHC) moiety (PICBNHC-Pd) have been developed, wherein the NHC moiety plays dual roles as a crosslinker and a ligand to activate the Pd NPs. The presence of both Pd NPs and NHC was confirmed by STEM/EDS and SR-MAS NMR analyses, respectively. This PICB-NHC-Pd catalyst showed excellent activity in the Suzuki-Miyaura coupling reaction without leaching of Pd. Excellent results were obtained in gram-scale synthesis, and catalyst recovery/reuse experiments were completed without loss of catalyst activity.
