78431-47-7 Usage
Description
(3R,3aR)-2-acetyl-8-methoxy-5-[(4-methylphenyl)sulfonyl]-3-pyridin-4-yl-3,3a,4,5-tetrahydro-2H-pyrazolo[4,3-c]quinoline is a complex organic compound characterized by its unique molecular structure that features pyridine, quinoline, and tetrahydro-pyrazolo rings. It also incorporates a sulfonyl group, an acetyl group, a methoxy group, and a methylphenyl substituent. (3R,3aR)-2-acetyl-8-methoxy-5-[(4-methylphenyl)sulfonyl]-3-pyridin-4-yl-3,3a,4,5-tetrahydro-2H-pyrazolo[4,3-c]quinoline may possess pharmacological properties due to its structural features, making it a promising candidate for further research in medicinal chemistry and drug development.
Uses
Used in Medicinal Chemistry:
(3R,3aR)-2-acetyl-8-methoxy-5-[(4-methylphenyl)sulfonyl]-3-pyridin-4-yl-3,3a,4,5-tetrahydro-2H-pyrazolo[4,3-c]quinoline is used as a compound of interest for its potential pharmacological properties, which may be harnessed for the development of new drugs and therapeutic agents.
Used in Drug Development:
In the field of drug development, (3R,3aR)-2-acetyl-8-methoxy-5-[(4-methylphenyl)sulfonyl]-3-pyridin-4-yl-3,3a,4,5-tetrahydro-2H-pyrazolo[4,3-c]quinoline is utilized for its potential to contribute to the discovery and design of novel pharmaceuticals, given its intricate molecular structure and the presence of various functional groups that could interact with biological targets.
Check Digit Verification of cas no
The CAS Registry Mumber 78431-47-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,4,3 and 1 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 78431-47:
(7*7)+(6*8)+(5*4)+(4*3)+(3*1)+(2*4)+(1*7)=147
147 % 10 = 7
So 78431-47-7 is a valid CAS Registry Number.
78431-47-7Relevant articles and documents
Studies in Antifertility Agents: Part XXXII-Synthesis and Stereochemistry of 3,3a-trans- and cis-2(H)-Acetyl-3-aryl-3,3a-dihydropyrazolochromenes, Pyrazolobenzocycloalk-1-enes and 3,3a-trans- and cis-(2H)-Acetyl-3-aryl-8-methoxy-5-tosyl-3,3a,4,5-tetrahydropyrazolo<4,...
Sangwan, Naresh K.,Rastogi, Shri Nivas
, p. 135 - 139 (2007/10/02)
Condensation of 4-chromanones (1,2), benzocycloalkan-1-ones (3,4) and N-tosyl-6-methoxy-2,3-dihydro-4-quinolone (5) with araldehydes ( 6-9) in the presence of HCl, KOH and NaOMe respectively gives the corresponding arylideno-ketones (10-17).These arylidenes (10-17) when refluxed with NH2-NH2*H2O in AcOH furnish the title compounds, 3,3a-trans- and cis-2(H)-acetyl-3-aryl-3,3a-dihydropyrazolochromenes (18a,b-21a,b), pyrazolobenzocycloalk-1-enes (22a,b-23a,b), and 3,3a-trans- and cis-2(H)-acetyl-3-aryl-8-methoxy-5-tosyl-3,3a,4,5-tetrahydropyrazoloquinolines (24a,b-25a,b).This cis- and trans-isomers have been separated by column chromatography over silica gel or by fractional crystallization and their stereochemistry has been assigned on the basis of PMR decoupling studies.Refluxing of 3-benzylidene-4-chromanone (10) with PhNHNH2 furnishes 3,3a-trans-2,3-diphenyl-3,3a-dihydropyrazolochromene (26).Treatment of 4 with NH2NH2*H2O in AcOH affords its acethydrazone derivative (27).The trans- and cis-mixtures of compounds 24 and 25 show antiimplantation activity at 20 mg/kg dose in female albino rats.
