78706-09-9 Usage
Description
(Z)-N-hydroxy-1-pyrrolo[2,3-c]carbazol-1(6H)-ylidenemethanamine, also known as HPC, is a chemical compound that belongs to the class of N-hydroxyguanine adducts. These adducts are a type of DNA damage that occurs when guanine reacts with electrophilic N-nitroso compounds. HPC specifically forms in the presence of the common mutagenic nitrosamine N-nitrosopyrrolidine. It has been identified as a potential biomarker for DNA damage due to exposure to nitrosamines, and studying its molecular structure and properties could offer valuable insights into the mechanisms of nitrosamine-induced carcinogenesis.
Uses
Used in Biomarker Research:
(Z)-N-hydroxy-1-pyrrolo[2,3-c]carbazol-1(6H)-ylidenemethanamine is used as a biomarker for [detecting DNA damage resulting from exposure to nitrosamines] because [it forms specifically in the presence of mutagenic nitrosamines like N-nitrosopyrrolidine].
Used in Cancer Research:
(Z)-N-hydroxy-1-pyrrolo[2,3-c]carbazol-1(6H)-ylidenemethanamine is used as a research tool for [understanding the mechanisms of nitrosamine-induced carcinogenesis] due to [its formation as a result of guanine reacting with electrophilic N-nitroso compounds].
Used in Drug Development:
(Z)-N-hydroxy-1-pyrrolo[2,3-c]carbazol-1(6H)-ylidenemethanamine is used as a potential target for [developing new strategies for cancer prevention and treatment] as [it may have implications for mitigating the harmful effects of nitrosamine exposure].
Used in Environmental and Occupational Health:
(Z)-N-hydroxy-1-pyrrolo[2,3-c]carbazol-1(6H)-ylidenemethanamine is used as an indicator for [assessing the risk of nitrosamine exposure in various settings] because [it serves as a biomarker for DNA damage from nitrosamines].
Check Digit Verification of cas no
The CAS Registry Mumber 78706-09-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,7,0 and 6 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 78706-09:
(7*7)+(6*8)+(5*7)+(4*0)+(3*6)+(2*0)+(1*9)=159
159 % 10 = 9
So 78706-09-9 is a valid CAS Registry Number.
