78710-80-2 Usage
Description
(Cyclobutylsulfonyl)benzene, with the molecular formula C10H12O2S, is a sulfonylbenzene derivative featuring a cyclobutyl group attached to the sulfonyl moiety. This chemical compound serves as a versatile building block in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds.
Uses
Used in Pharmaceutical Industry:
(Cyclobutylsulfonyl)benzene is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, (Cyclobutylsulfonyl)benzene is utilized as a precursor for the development of novel compounds with pesticidal, herbicidal, or fungicidal properties, contributing to enhanced crop protection and yield.
Used in Organic Synthesis:
(Cyclobutylsulfonyl)benzene is employed as a building block for the preparation of functionalized benzenes and sulfones, which are essential in the creation of a wide range of organic compounds with diverse applications.
Used in Research and Development:
Due to its potential for biological activity, (Cyclobutylsulfonyl)benzene is under investigation for its pharmacological properties. Researchers are exploring its possible applications in the development of new drugs and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 78710-80-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,7,1 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 78710-80:
(7*7)+(6*8)+(5*7)+(4*1)+(3*0)+(2*8)+(1*0)=152
152 % 10 = 2
So 78710-80-2 is a valid CAS Registry Number.
78710-80-2Relevant articles and documents
Base-Mediated Radical Borylation of Alkyl Sulfones
Huang, Mingming,Hu, Jiefeng,Krummenacher, Ivo,Friedrich, Alexandra,Braunschweig, Holger,Westcott, Stephen A.,Radius, Udo,Marder, Todd B.
, (2021/12/02)
A practical and direct method was developed for the production of versatile alkyl boronate esters via transition metal-free borylation of primary and secondary alkyl sulfones. The key to the success of the strategy is the use of bis(neopentyl glycolato) diboron (B2neop2), with a stoichiometric amount of base as a promoter. The practicality and industrial potential of this protocol are highlighted by its wide functional group tolerance, the late-stage modification of complex compounds, no need for further transesterification, and operational simplicity. Radical clock, radical trap experiments, and EPR studies were conducted which show that the borylation process involves radical intermediates.
A new stereoselective synthesis of (±)-grandisol based on the remote alkylation protocol
Monteiro, Hugo J.,Stefani, Helio A.
, p. 2659 - 2663 (2007/10/03)
A new stereoselective synthesis of (±)-grandisol (1a) has been developed. The synthesis starts with a simple cyclobutyl derivative to which the methyl group and the 1,2-cis disposed side chains were appended through a remote alkylation protocol.
Reductive Lithiation of Bis-Phenylsulfones
Mioskowski, Charles
, p. 5437 - 5440 (2007/10/02)
Reductive cleavage of geminal bis-phenylsulfones using lithium naphthalenide in THF at -78 degC selectively affords α-sulfonyl carbanions which participate in typical reaction with electrophiles. - Key words: desulfonylation, lithium naphthalenide, alkyla
