791642-68-7

Basic information

• Product Name: 4-bromo-1-iodo-2-methoxybenzene
• Synonyms: 4-bromo-1-iodo-2-methoxybenzene;Benzene, 4-broMo-1-iodo-2-Methoxy-;4-Bromo-1-iodo-2-methoxybenzene, 5-Bromo-2-iodophenyl methyl ether;5-Bromo-2-iodoanisole 97%;5-BroMo-2-iodoanisole;5-Bromo-2-iodoanisole97%
• CAS NO: 791642-68-7
• Molecular Formula: C₇H₆BrIO
• Molecular Weight: 312.927
• Mol File: 791642-68-7.mol
• Article Data: 16

Chemical Properties

• Melting Point: 37 °C
• Boiling Point: 161-162 °C(Press: 8 Torr)
• Appearance: /
• Density: 2.062±0.06 g/cm3(Predicted)
• Refractive Index: 1.624
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 4-bromo-1-iodo-2-methoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-1-iodo-2-methoxybenzene(791642-68-7)
• EPA Substance Registry System: 4-bromo-1-iodo-2-methoxybenzene(791642-68-7)

Safety Data

• Hazardous Substances Data: 791642-68-7(Hazardous Substances Data)

Usage

Description

4-bromo-1-iodo-2-methoxybenzene is an organic compound characterized by the presence of a benzene ring with a bromine atom at the 4th position, an iodine atom at the 1st position, and a methoxy group at the 2nd position. 4-bromo-1-iodo-2-methoxybenzene is known for its potential applications in various chemical and pharmaceutical processes due to its unique structural features.

Uses

Used in Pharmaceutical Industry:
4-bromo-1-iodo-2-methoxybenzene is used as a key intermediate in the synthesis of arylsulfanylphenyloxyalkylamino acids, which serve as GlyT-1 inhibitors. GlyT-1 inhibitors are important in the development of treatments for various neurological disorders, such as schizophrenia and major depressive disorder, by modulating the levels of glycine in the brain.
Additionally, 5-bromo-2-iodoanisole, a related compound, is also used in the preparation of arylsulfanylphenyloxyalkylamino acids as GlyT-1 inhibitors, further highlighting the utility of these compounds in the pharmaceutical industry.

InChI:InChI=1/C7H6BrIO/c1-10-7-4-5(8)2-3-6(7)9/h2-4H,1H3

Upstream product

• 59557-91-4 4-bromo-2-methoxyaniline 
• 93-27-6 5-nitro-2-acetylaminoanisole 
• 5329-15-7 N-(4-amino-2-methoxyphenyl)acetamide 
• 90-04-0 2-methoxy-phenylamine 
• 2398-37-0 3-methoxyphenyl bromide 
• 72135-36-5 4-bromo-2-methoxybenzoic acid 
• 858855-11-5 5-bromo-2-iodo-phenol 
• 74-88-4 methyl iodide 

Downstream Products

• 905815-85-2 5-bromo-2-(3-fluoro-phenylsulfanyl)-1-methoxybenzene 
• 905815-92-1 5-bromo-2-(3-fluoro-phenylsulfanyl)-phenol 
• 905816-01-5 2-[5-bromo-2-(3-fluoro-phenylsulfanyl)-phenoxy]-ethanol 
• 791644-01-4 (S)-1-{2-[5-bromo-2-(3-fluoro-phenylsulfanyl)-phenoxy]-ethyl}-pyrrolidine-2-carboxylic acid tert-butyl ester 
• 1027100-80-6 C₃₄H₂₅BrO₄ 
• 870838-56-5 1-(4-bromo-2-methoxyphenyl)-4-methyl-1H-imidazole 
• 1167993-66-9 1-(4-bromo-2-methoxyphenyl)-2-(4-tolyl)ethyne 
• 889849-21-2 (4-bromo-2-methoxyphenyl)boronic acid 
• 1264728-53-1 4-(4-bromo-2-methoxyphenoxy)-3,6-di((S)-sec-butyl)-3-hydroxy-1-methoxypiperazine-2,5-dione 
• 1264728-54-2 4-(4-bromo-2-methoxyphenoxy)-3,6-di((S)-sec-butyl)-1,3-dimethoxypiperazine-2,5-dione 
• 90965-63-2 4-bromocyclohexa-3,5-diene-1,2-dione 
• 1264728-46-2 4-bromo-2-methoxy-1-(bisacetoxyiodo)benzene 
• 1146245-82-0 C₂₄H₂₂F₃N₅O 
• 1145785-48-3 N-[(1S)-1-(4-fluorophenyl)propyl]-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]-3-pyridazinamine 

Relevant articles and documents

3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

SALT OF HALOGEN-SUBSTITUTED HETEROCYCLIC COMPOUND

The invention provides a novel α-halogen-substituted thiophene compound salt that has a potent LPA receptor antagonistic action and is useful as a medicament. The salt is represented by the general formula (I): (wherein R is a hydrogen atom or a methoxy g

HALOGEN-SUBSTITUTED HETEROCYCLIC COMPOUND

A novel α-halogen-substituted thiophene compound or a pharmacologically acceptable salt thereof, which has a potent LPA receptor-antagonist activity and is useful as a medicament is provided. A compound represented by the general formula (I) wherein A represents, a phenyl ring, a thiophene ring, or an isothiazole ring; R1 is the same or different, and represents a halogen atom, or a C1-C3 alkyl group; R2 represents a hydrogen atom, or a C1-C6 alkyl group; p represents an integer of 0 to 5; V represents CR3 wherein R3 represents a hydrogen atom, an amino group, a nitro group, or a C1-C3 alkoxy group, or V represents a nitrogen atom; and X represents a halogen atom, or a salt thereof.