791644-59-2

Basic information

• Product Name: 3-Fluoro-5-(3-pyridinyloxy)benzenamine
• Synonyms: 3-Fluoro-5-(3-pyridinyloxy)benzenamine;3-Fluoro-5-(pyridin-3-yloxy)aniline;3-fluoro-5-(pyridin-3-yloxy)benzenamine;3-Fluoro-5-(pyridin-3-yloxy)-phenylamine
• CAS NO: 791644-59-2
• Molecular Formula: C₁₁H₉FN₂O
• Molecular Weight: 204.203
• Mol File: 791644-59-2.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-Fluoro-5-(3-pyridinyloxy)benzenamine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Fluoro-5-(3-pyridinyloxy)benzenamine(791644-59-2)
• EPA Substance Registry System: 3-Fluoro-5-(3-pyridinyloxy)benzenamine(791644-59-2)

Safety Data

• Hazardous Substances Data: 791644-59-2(Hazardous Substances Data)

Usage

General Description

3-Fluoro-5-(3-pyridinyloxy)benzenamine is a chemical compound that consists of a fluorine atom, a pyridine ring, and an amine group attached to a benzene ring. It is commonly used in pharmaceutical and agrochemical industries as a building block for the synthesis of various organic compounds. This chemical has potential applications in the development of new drugs, pesticides, and herbicides. It may also be used as a reagent in organic chemistry reactions to introduce specific functional groups into molecules. The compound's structure and properties make it a versatile and useful tool for researchers and chemists in various fields.

Upstream product

• 803700-29-0 3-(3-fluoro-5-nitrophenoxy)pyridine 
• 109-00-2 3-HYDROXYPYRIDINE 
• 2265-94-3 1,3-difluoro-5-nitrobenzene 

Downstream Products

• 1245607-31-1 2-(3-fluoro-5-(pyridin-3-yloxy)phenyl)isoindoline-1,3-dione 
• 1245607-46-8 methyl 2-(N-(3-fluoro-5-(pyridin-3-yloxy)phenyl)sulfamoyl)benzoate 
• 1241384-85-9 C₁₈H₁₃F₂N₃O₂ 
• 1245607-47-9 N-(3-fluoro-5-(pyridin-3-yloxy)phenyl)-2-(hydroxymethyl)benzenesulfonamide 
• 1245607-30-0 2-(3-fluoro-5-(pyridin-3-yloxy)phenyl)-2,3-dihydrobenzo[d]isothiazole-1,1-dioxide 

Relevant articles and documents

Non-Acidic Free Fatty Acid Receptor 4 Agonists with Antidiabetic Activity

The free fatty acid receptor 4 (FFA4 or GPR120) has appeared as an interesting potential target for the treatment of metabolic disorders. At present, most FFA4 ligands are carboxylic acids that are assumed to mimic the endogenous long-chain fatty acid agonists. Here, we report preliminary structure-activity relationship studies of a previously disclosed nonacidic sulfonamide FFA4 agonist. Mutagenesis studies indicate that the compounds are orthosteric agonists despite the absence of a carboxylate function. The preferred compounds showed full agonist activity on FFA4 and complete selectivity over FFA1, although a significant fraction of these noncarboxylic acids also showed partial antagonistic activity on FFA1. Studies in normal and diet-induced obese (DIO) mice with the preferred compound 34 showed improved glucose tolerance after oral dosing in an oral glucose tolerance test. Chronic dosing of 34 in DIO mice resulted in significantly increased insulin sensitivity and a moderate but significant reduction in bodyweight, effects that were also present in mice lacking FFA1 but absent in mice lacking FFA4.

NOVEL ISOINDOLIN-1-ONE DERIVATIVE

The present invention relates to a compound represented by formula (I): (wherein R1, R2, R3 and R4 each independently represent a hydrogen or halogen atom; R5 and R6 each independently represent a hydrogen atom or lower alkyl or together represent oxo; X represents C(O) or the like; Y represents an oxygen atom or the like; Z represents a hydrogen atom or the like; R represents 5- or 6-membered heteroaryl having 1-3 hetero atoms selected from the group consisting of nitrogen, sulfur and oxygen atoms, contained within a ring, or the like) or to a pharmaceutically acceptable salt thereof.