79171-94-1

Basic information

• Product Name: Biphenyl-4-carboxylic acid (3aR,4R,5R,6aS)-4-[(E)-4-(4-chloro-phenoxy)-3-oxo-but-1-enyl]-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester
• Synonyms: Biphenyl-4-carboxylic acid (3aR,4R,5R,6aS)-4-[(E)-4-(4-chloro-phenoxy)-3-oxo-but-1-enyl]-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester
• CAS NO: 79171-94-1
• Molecular Weight: 516.978
• Mol File: 79171-94-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Biphenyl-4-carboxylic acid (3aR,4R,5R,6aS)-4-[(E)-4-(4-chloro-phenoxy)-3-oxo-but-1-enyl]-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Biphenyl-4-carboxylic acid (3aR,4R,5R,6aS)-4-[(E)-4-(4-chloro-phenoxy)-3-oxo-but-1-enyl]-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester(79171-94-1)
• EPA Substance Registry System: Biphenyl-4-carboxylic acid (3aR,4R,5R,6aS)-4-[(E)-4-(4-chloro-phenoxy)-3-oxo-but-1-enyl]-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester(79171-94-1)

Safety Data

• Hazardous Substances Data: 79171-94-1(Hazardous Substances Data)

Upstream product

• 40665-86-9 dimethyl 3-(4-chlorophenoxy)-2-oxopropylphosphonate 
• 38754-71-1 (3aR,4R,5R,6aS)-4-formyl-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl biphenyl-4-carboxylate 

Downstream Products

• 79124-67-7 N-(methanesulfonyl)-16-(p-chlorophenoxy)-ω-tetranor-PGE₂-carboxamide 
• 79124-54-2 (3aR,4R,5R,6aS)-4-[(E)-(R)-4-(4-Chloro-phenoxy)-3-(tetrahydro-pyran-2-yloxy)-but-1-enyl]-5-(tetrahydro-pyran-2-yloxy)-hexahydro-cyclopenta[b]furan-2-ol 
• 444084-22-4 (3aR,4R,5R,6aS)-4-[(E)-(R)-4-(4-Chloro-phenoxy)-3-hydroxy-but-1-enyl]-5-hydroxy-hexahydro-cyclopenta[b]furan-2-one 
• 40667-56-9 Biphenyl-4-carboxylic acid (3aR,4R,5R,6aS)-4-[(E)-(S)-4-(4-chloro-phenoxy)-3-hydroxy-but-1-enyl]-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester 
• 40667-56-9 Biphenyl-4-carboxylic acid (3aR,4R,5R,6aS)-4-[(E)-(R)-4-(4-chloro-phenoxy)-3-hydroxy-but-1-enyl]-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester 

Relevant articles and documents

N-(Methanesulfonyl)-16-phenoxyprostaglandincarboxamides: Tissue-Selective, Uterine Stimulants

In an effort to develop tissue-selective prostaglandin analogues resistant to the metabolic inactivating pathways of the natural materials, hybrid compounds modified both at C-1 with a sulfonimide moiety and in the n-amylcarbinol side chain with substituted phenoxy groups were synthesized and evaluated in a variety of in vitro and in vivo models.Several of these analogues exhibited potent, tissue-selective, uterine stimulant activity, a finding subsequently confirmed in clinical studies with one member of this series, N-(methanesulfonyl)-16-phenoxy-ω-tetranor-PGE2-carboxamide (CP-34089/ZK-57671, sulprostone).