791828-58-5 Usage
Uses
Aderbasib is a azaspiro[2.5]octanehydroxamide derivative as inhibitor of metalloproteases for the treatment of disorders such as cancer, arthritis, cardiovascular or skin disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 791828-58-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,9,1,8,2 and 8 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 791828-58:
(8*7)+(7*9)+(6*1)+(5*8)+(4*2)+(3*8)+(2*5)+(1*8)=215
215 % 10 = 5
So 791828-58-5 is a valid CAS Registry Number.
791828-58-5Relevant articles and documents
AZA SPIRO ALKANE DERIVATIVES AS INHIBITORS OF METALLPROTEASES
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, (2015/12/18)
The present invention provides a compound of Formula (I) or Formula (II): enantiomer, diastereomer, prodrug, solvate, metabolite, or pharmaceutically acceptable salt thereof, wherein constituent variables are provided herein. The compounds of Formula (I) and (II) are modulators of metalloproteases and are useful in treating diseases associated with metalloprotease activity such as arthritis, cancer, cardiovascular disorders, skin disorders, inflammation and allergic conditions.
