79373-03-8

Basic information

• Product Name: 2-BIPHENYL-4-YL-INDOLIZINE
• Synonyms: 2-BIPHENYL-4-YL-INDOLIZINE;2-{[1,1-biphenyl]-4-yl}indolizine
• CAS NO: 79373-03-8
• Molecular Formula: C₂₀H₁₅N
• Molecular Weight: 269.34
• Mol File: 79373-03-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.07g/cm³
• Refractive Index: 1.621
• CAS DataBase Reference: 2-BIPHENYL-4-YL-INDOLIZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BIPHENYL-4-YL-INDOLIZINE(79373-03-8)
• EPA Substance Registry System: 2-BIPHENYL-4-YL-INDOLIZINE(79373-03-8)

Safety Data

• Hazardous Substances Data: 79373-03-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C20H15N/c1-2-6-16(7-3-1)17-9-11-18(12-10-17)19-14-20-8-4-5-13-21(20)15-19/h1-15H

Upstream product

• 109-06-8 α-picoline 
• 135-73-9 2-Bromo-4'-phenylacetophenone 
• 92-91-1 biphenyl-4-acetaldehyde 

Relevant articles and documents

Oxidation Potential-Guided Electrochemical Radical-Radical Cross-Coupling Approaches to 3-Sulfonylated Imidazopyridines and Indolizines

Oxidation potential-guided electrochemical radical-radical cross-coupling reactions between N-heteroarenes and sodium sulfinates have been established. Thus, simple cyclic voltammetry measurement of substrates predicts the likelihood of successful radical-radical coupling reactions, allowing the simple and direct synthetic access to 3-sulfonylated imidazopyridines and indolizines. The developed electrochemical radical-radical cross-coupling reactions to sulfonylated N-heteroarenes boast the green synthetic nature of the reactions that are oxidant- and metal-free.

Transition-Metal-Free Regioselective Cross-Coupling: Controlled Synthesis of Mono- or Dithiolation Indolizines

An efficient transition-metal-free regioselective C-H/S-H cross-coupling of indolizines with thiols has been developed for the first time to describe a workable route to indolizine thioethers. This finding provides a new method and more straightforward pathway for controllable synthesis of mono- or dithiolation indolizines that are otherwise difficult to obtain by the literature methods. The reaction exhibits good functional group tolerance and high efficiency and affords the products in good to excellent yields.