79386-90-6

Basic information

• Product Name: 1,5-dichloropentan-2-one
• CAS NO: 79386-90-6
• Molecular Formula: C₅H₈Cl₂O
• Molecular Weight: 155.0224
• Mol File: 79386-90-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 218.8°C at 760 mmHg
• Flash Point: 87.5°C
• Density: 1.183g/cm³
• Vapor Pressure: 0.124mmHg at 25°C
• Refractive Index: 1.446
• CAS DataBase Reference: 1,5-dichloropentan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-dichloropentan-2-one(79386-90-6)
• EPA Substance Registry System: 1,5-dichloropentan-2-one(79386-90-6)

Safety Data

• Hazardous Substances Data: 79386-90-6(Hazardous Substances Data)

Usage

Physical state

Clear, colorless liquid

Odor

Strong

Usage

Intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds

Additional use

Solvent in various chemical processes

Safety concerns

Potentially harmful if ingested or inhaled

Precautions

Necessary when handling and storing the compound

Upstream product

• 186581-53-3 diazomethane 
• 4635-59-0 4-Chlorobutanoyl chloride 
• 75-19-4 cyclopropane 
• 79-04-9 chloroacetyl chloride 
• 7446-70-0 aluminium trichloride 
• 67-66-3 chloroform 

Downstream Products

• 851286-21-0 3-(5-chloro-2-oxo-pentylsulfanyl)-4-(5-chloro-2-hydroxy-phenyl)-6-trifluoromethyl-1H-quinolin-2-one 
• 522648-84-6 1-[3-(6-bromobenzo[b]thiophene-3-yl)propyl]-4-(2-methoxyphenyl)piperazine 
• 522648-82-4 1-[3-(4-bromobenzo[b]thiophene-3-yl)propyl]-4-(2-methoxyphenyl)piperazine 
• 1577-22-6 5-hexenoic acid 
• 144121-60-8 1-phenylhex-5-en-1-ol 

Relevant articles and documents

4'-AMINO CYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY

The present disclosure provides compounds having affinity for the 5-HT6 receptor which are of the formula (I): formula (I) wherein Cy is selected from formula (Il) and wherein R1, R2, R3, Q, G, Ar, m, n and p are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

Lithium or Bromomagnesium 1,4- and 1,5-Dilithioalkan-2-yloxides: Preparation and Synthetic Applications

Treatment of chloromethyl 2- or 3-chloroalkyl carbinols with butyllithium and then lithium naphthalenide or with ethylmagnesium bromide and then powdered lithium leads to the formation of lithium or bromomagnesium dilithiothioalkoxides, respectively, which represent trianionic species.The bromomagnesium 1,ω-dilithio-2-alkoxides undergo immediate elimination of lithium bromide and magnesium oxide to give ω-lithio-1-alkenes.These latter organometallic compounds as well as the lithium dithioalkoxides react with various electrophiles to afford functionalized compounds.