79421-46-8

Basic information

• Product Name: 4-(4-oxopiperidin-1-yl)benzonitrile
• Synonyms: 4-(4-oxopiperidin-1-yl)benzonitrile;4-(4-oxo-1-piperidinyl)benzonitrile
• CAS NO: 79421-46-8
• Molecular Formula: C₁₂H₁₂N₂O
• Molecular Weight: 200.23648
• Mol File: 79421-46-8.mol
• Article Data: 18

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(4-oxopiperidin-1-yl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-oxopiperidin-1-yl)benzonitrile(79421-46-8)
• EPA Substance Registry System: 4-(4-oxopiperidin-1-yl)benzonitrile(79421-46-8)

Safety Data

• Hazardous Substances Data: 79421-46-8(Hazardous Substances Data)

Upstream product

• 1194-02-1 4-fluorobenzonitrile 
• 41979-39-9 4-piperidone hydrochloride 
• 79421-43-5 N-(4-cyanophenyl)-4-hydroxypiperidine 
• 79421-39-9 4-(1,4-dioxa-8-aza-spiro[4.5]dec-8-yl)-benzonitrile 
• 5382-16-1 4-HYDROXYPIPERIDINE 
• 177-11-7 4,4-ethylenedioxy-piperidine 

Downstream Products

• 134348-58-6 C₂₃H₂₂N₄ 
• 182201-44-1 N-(4-cyanophenyl)-4-(4-cyanobenzylidinyl)piperidine 
• 182201-45-2 C₂₀H₁₉N₃ 
• 870812-38-7 4-(4-benzyl-4-hydroxy-1-piperidinyl)benzonitrile 
• 870812-54-7 4-(4-(4-fluorobenzylidene)-1-piperidinyl)benzonitrile 
• 218610-46-9 (2-(1-(4-Cyanophenyl)piperidin-4-ylamino)ethyl)carbamic acid tert-butyl ester 
• 116248-02-3 4-(10-chloro-3,4-dihydrobenzo[b][1,6]-naphthyridin-2(1H)-yl)benzoic acid ethyl ester 
• 1334721-51-5 C₁₃H₁₄N₂ 
• 1449429-05-3 2-amino-6-(4-cyanophenyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carbonitrile 
• 1449428-72-1 2,4-dichloro-N-(3-cyano-6-(4-cyanophenyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-5-(morpholinosulfonyl)benzamide 
• 218610-47-0 4-(4-(2-Aminoethylamino)piperidin-1-yl)benzonitrile 

Relevant articles and documents

Anti-Inflammation Compounds

The present invention refers to: a compound having the general formula (I), wherein n is 0, 1, 2 or; m is 0, 1, 2 or 3; o is 0, 1, 2 or 3; W, X, Y and Z are independently selected from CH, N or N-oxide; A is NR4, C═O, C═S, OP(O)(O), P═O, CH2, or a heteroarly selected from the group consisting of (a), (b), (c), (d), (e), (f), (g); V is C═O, O, S, CH2, or NR5; as well as its use in treating inflammatory diseases such as asthma, COPD, inflammation post infection, arthritis, atherosclerosis, pain and dermatitis.

ANTI-INFECTIVE COMPOUNDS

The present invention relates to small molecule compounds and their use in the treatment of bacterial infections, in particular Tuberculosis.

SUBSTITUTED (AMINOIMINOMETHYL OR AMINOMETHYL) BENZOHETEROARYL COMPOUNDS

This invention is directed to an (aminoiminomethyl or aminomethyl) benzoheteroaryl compound of formula I which is useful for inhibiting the activity of Factor Xa by combining said compound with a composition containing Factor Xa. The present invention is also directed to compositions containing compounds of the formula I, methods for their preparation, their use, such as in inhibiting the formation of thrombin or for treating a patient suffering from, or subject to, a disease state associated with a physiologically detrimental excess amount of thrombin.