79421-99-1

Basic information

• Product Name: Boroxin, tris(3-methoxyphenyl)-
• CAS NO: 79421-99-1
• Molecular Formula: C21H21B3O6
• Molecular Weight: 401.827
• Mol File: 79421-99-1.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: Boroxin, tris(3-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Boroxin, tris(3-methoxyphenyl)-(79421-99-1)
• EPA Substance Registry System: Boroxin, tris(3-methoxyphenyl)-(79421-99-1)

Safety Data

• Hazardous Substances Data: 79421-99-1(Hazardous Substances Data)

Upstream product

• 13195-76-1 triisobutyl borate 
• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 10365-98-7 3-methoxyphenylboronic acid 

Downstream Products

• 1224738-22-0 N-benzyl-3,4-dihydro-4-(3-methoxyphenyl)quinolin-2(1H)-one 
• 32040-09-8 4-(3-methoxyphenyl)morpholine 
• 56511-50-3 N-(3-methoxyphenyl)dibenzylamine 
• 840529-73-9 (R)-N-[(3-methoxyphenyl)phenylmethyl]-4-nitrobenzenesulfonamide 
• 456-49-5 1-fluoro-3-methoxybenzene 
• 100-66-3 methoxybenzene 
• 59424-91-8 2,2,2-trichloro-1-(3-methoxyphenyl)ethan-1-ol 

Relevant articles and documents

Nickel(II)-Catalyzed Addition of Aryl and Heteroaryl Boroxines to the Sulfinylamine Reagent TrNSO: The Catalytic Synthesis of Sulfinamides, Sulfonimidamides, and Primary Sulfonamides

We report a redox-neutral Ni(II)-catalyzed addition of (hetero)aryl boroxines to N-sulfinyltritylamine (TrNSO). The reactions use a catalyst generated from the combination of commercial, air-stable NiCl2·(glyme) and a commercially available bipyridine lig

Rhodium-Catalyzed Enantioposition-Selective Hydroarylation of Divinylphosphine Oxides with Aryl Boroxines

The rhodium-catalyzed hydroarylation of divinylphosphine oxides (RP(O)(CH=CH2)2) with aryl boroxines ((ArBO)3) gives the corresponding monoarylation products (RP(O)(CH=CHAr)CH2CH3) in high yields. One of the two vinyl groups in the phosphine oxide undergoes oxidative arylation while the other one is reduced to an ethyl moiety. These reactions proceed with high selectivity in terms of the enantiotopic vinyl groups in the presence of (R)-DTBM-segphos/Rh to give the P-stereogenic monoarylation products with high enantioselectivity.

Palladium(II)-Catalyzed Enantioselective Synthesis of α-(Trifluoromethyl)arylmethylamines

We describe a method for the synthesis of α-(trifluoromethyl)arylmethylamines that consists of the palladium(II)-catalyzed addition of arylboroxines to imines derived from trifluoroacetaldehyde. Palladium acetate is used as a catalyst with electron-neutral or electron-rich arylboroxines, and it was found that addition of an ammonium or silver salt was crucial to promote the reaction of electron-poor boroxines. With (S)-t-Bu-PyOX as the chiral ligand, this method delivers a variety of α-trifluoromethylated amines in 57-91% yield and with greater than 92% ee in most cases.