794452-00-9 Usage
General Description
2-Cyclopropyl-4,5,6,7-tetrahydrooxazolo[4,5-c]pyridine is a chemical compound that belongs to the oxazolopyridine class of compounds. It is a highly complex and heterocyclic molecule, featuring a cyclopropyl ring and oxazolo[4,5-c]pyridine core structure. 2-cyclopropyl-4,5,6,7-tetrahydrooxazolo[4,5-c]pyridine is used in pharmaceutical research and drug development due to its potential bioactivity and therapeutic applications. Its structure and properties make it a promising candidate for the development of new pharmaceuticals targeting various diseases and medical conditions. As with all chemical compounds, safety and proper handling procedures should be followed when working with 2-cyclopropyl-4,5,6,7-tetrahydrooxazolo[4,5-c]pyridine in a laboratory setting.
Check Digit Verification of cas no
The CAS Registry Mumber 794452-00-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,9,4,4,5 and 2 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 794452-00:
(8*7)+(7*9)+(6*4)+(5*4)+(4*5)+(3*2)+(2*0)+(1*0)=189
189 % 10 = 9
So 794452-00-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H12N2O/c1-2-6(1)9-11-7-5-10-4-3-8(7)12-9/h6,10H,1-5H2
794452-00-9Relevant articles and documents
Dipeptidyl peptidase IV inhibitors derived from β-aminoacylpiperidines bearing a fused thiazole, oxazole, isoxazole, or pyrazole
Ashton, Wallace T.,Sisco, Rosemary M.,Dong, Hong,Lyons, Kathryn A.,He, Huaibing,Doss, George A.,Leiting, Barbara,Patel, Reshma A.,Wu, Joseph K.,Marsilio, Frank,Thornberry, Nancy A.,Weber, Ann E.
, p. 2253 - 2258 (2007/10/03)
A series of β-aminoacylpiperidines bearing various fused five-membered heterocyclic rings was synthesized as dipeptidyl peptidase IV inhibitors. Potent and relatively selective inhibition could be obtained, depending on choice of heterocycle, regioisomerism, and substitution. In particular, one analog (74, DPP-IV IC50 = 26 nM) exhibited good oral bioavailability and acceptable half-life in the rat, albeit with rather high clearance.
