79739-22-3

Basic information

• Product Name: 6-CHLORO-[3,4']-BIPYRIDINE
• Synonyms: 6-CHLORO-[3,4']-BIPYRIDINE
• CAS NO: 79739-22-3
• Molecular Formula: C10H7ClN2
• Molecular Weight: 190.62898
• Mol File: 79739-22-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 323.1 °C at 760 mmHg
• Flash Point: 178.9 °C
• Appearance: /
• Density: 1.245 g/cm³
• CAS DataBase Reference: 6-CHLORO-[3,4']-BIPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLORO-[3,4']-BIPYRIDINE(79739-22-3)
• EPA Substance Registry System: 6-CHLORO-[3,4']-BIPYRIDINE(79739-22-3)

Safety Data

• Hazardous Substances Data: 79739-22-3(Hazardous Substances Data)

Usage

General Description

6-Chloro-[3,4']-bipyridine is a chemical compound prominently used in scientific research. It is characterized by the presence of a bipyridine structure with a chlorine atom attached to one of the carbon atoms. This chemical belongs to the family of Bipyridines and polyazamacrocycles. However, it bears specific usage limitations due to its toxic and irritating attributes. It is commonly prepared in the laboratory under controlled conditions and its handling requires adequate safety procedures. Currently, there is limited information regarding the applications of this chemical, indicating the need for further studies and research.

Upstream product

• 62749-34-2 1,2-dihydro-2-oxo-5-(4-pyridinyl)-pyridine 
• 106154-27-2 6'-methoxy-4,3'-bipyridine 
• 106154-29-4 6-benzyloxy-3,4'-bipyridine 

Downstream Products

• 79739-33-6 5-(4-pyridyl)pyridin-2-amine 

Relevant articles and documents

A CONVENIENT SYNTHESIS OF 3,4'-BIPYRIDINE

3,4'-Bipyridine was synthesized from 6-methoxy-3,4'-bipyridine or 6-benzyloxy-3,4'-bipyridine via 6-chloro-3,4'-bipyridine.The chloro derivative was catalytically dechlorinated into the corresponding 3,4'-bipyridine.

5-(Pyridinyl)pyridine-2-hydrazines, their preparation and their cardiotonic use

2-[R1 NHN(R)]-3-Q'-5-Py-6-Q-pyridines or pharmaceutically-acceptable acid-addition salts thereof are useful as cardiotonic agents, where Q is hydrogen or lower-alkyl, PY is 4- or 3-pyridinyl or 4- or 3-pyridinyl having one or two lower-alkyl substituents, Q' is hydrogen or halo, R is hydrogen, lower-alkyl or lower-hydroxyalkyl, and R1 is hydrogen or when R is other than hydrogen R1 is the same as R. These compounds are prepared by reacting a 2-halo-3-Q'-5-PY-6-Q-pyridine with R1 NHNHR where 2-halo is bromo or chloro. Also shown are: the use of said 2-[R1 NN(R)]-3-Q'-5-PY-6-Q-pyridines as cardiotonic agents; and, the intermediates, 2,3-dihalo-5-PY-6-Q-pyridines, and their preparation from 3-nitro-5-PY-6-Q-2(1H)-pyridinones.

1,3-Dihydro-6-(pyridinyl)-2H-imidazo[4,5-b]pyridin-2-ones and -imidazo[4,5-b]pyridine-2-thiones and their cardiotonic use

1,3-Dihydro-1-R1 -3-R3 -6-PY-5-Q-2H-imidazo[4,5-b]pyridin-2-ones or -2-thiones or pharmaceutically-acceptable acid-addition salts thereof, which are useful as cardiotonic agents, where Q is hydrogen or lower-alkyl, R1 and R3 are each hydrogen, lower-alkyl, lower-hydroxyalkyl, 2,3-dihydroxypropyl, lower-alkoxyalkyl or Y-NB where Y is lower-alkylene and NB is di-(lower-alkyl)amino or 4-morpholinyl, at least one of R1 and R3 being hydrogen, and PY is 4- or 3-pyridinyl or 4- or 3-pyridinyl having one or two substituents, are prepared by reacting a 2-R3 NH-3-R1 NH-5-PY-6-Q-pyridine with urea or carbonyldiimidazole to produce said -2-one or with an alkali metal xanthate, thiourea or thiocarbonyldiimidazole to produce said -2-thione. Also shown and claimed are cardiotonic compositions and a method for increasing cardiac contractility using said cardiotonic agents. Also shown are processes for preparing said intermediate 2-R3 NH-3-R1 NH-5-PY-6-Q-pyridines and other intermediates used in said processes.