797755-07-8 Usage
Description
Phenylacetic acid-4-boronic acid pinacol ester is an organic compound that serves as a versatile intermediate in the synthesis of various pharmaceuticals and materials. It is characterized by the presence of a phenylacetic acid group, a boronic acid functionality, and a pinacol ester moiety, which contribute to its unique reactivity and properties.
Uses
Used in Pharmaceutical Synthesis:
Phenylacetic acid-4-boronic acid pinacol ester is used as an intermediate for the preparation of hydantoin-derived autotaxin inhibitors. Autotaxin is an enzyme involved in the regulation of cell motility and is implicated in various diseases, making it an important target for drug development.
Used in Reactive Oxygen Species (ROS)-Sensitive Materials:
Phenylacetic acid-4-boronic acid pinacol ester is used as a substrate in the synthesis of ROS-sensitive and H2O2-eliminating materials. By interlinking phenylboronic acid pinacol esters onto β-cyclodextrin, materials with unique properties can be created, which have potential applications in various fields, including medicine and environmental protection.
Used in FLT3 Kinase Inhibitor Synthesis:
Phenylacetic acid-4-boronic acid pinacol ester is used to prepare 5-aryl-2-aminopyridine derived FLT3 kinase inhibitors. FLT3 kinase is a receptor tyrosine kinase that plays a crucial role in hematopoiesis and is often mutated in acute myeloid leukemia. Inhibitors targeting FLT3 kinase have potential therapeutic applications in the treatment of this disease.
Check Digit Verification of cas no
The CAS Registry Mumber 797755-07-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,9,7,7,5 and 5 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 797755-07:
(8*7)+(7*9)+(6*7)+(5*7)+(4*5)+(3*5)+(2*0)+(1*7)=238
238 % 10 = 8
So 797755-07-8 is a valid CAS Registry Number.
InChI:InChI=1/C14H19BO4/c1-13(2)14(3,4)19-15(18-13)11-7-5-10(6-8-11)9-12(16)17/h5-8H,9H2,1-4H3,(H,16,17)
