797818-02-1Relevant articles and documents
An acyclic aminonaphthyridine-based receptor for carbohydrate recognition: Binding studies in competitive solvents
Mazik, Monika,Cavga, Hueseyin
, p. 3633 - 3638 (2007)
1H NMR spectroscopic and microcalorimetric titrations revealed that receptor 3b, consisting of three protonated 2-amino-1,8-naphthyridine units, binds N-acetylneuraminic acid (Neu5Ac), the most commonly occurring sialic acid, with high affinity
Molecular recognition of carbohydrates with acyclic pyridine-based receptors
Mazik, Monika,Radunz, Wolfgang,Boese, Roland
, p. 7448 - 7462 (2007/10/03)
The recognition capabilities of acyclic pyridine-based receptors toward monosaccharides were evaluated. Aminopyridine receptors based on the 2,4,6-trimethyl- or 2,4,6-triethylbenzene frame show high β vs α binding selectivity in the recognition of glucopyranosides. Amidopyridine receptors, which are sterically less hindered at nitrogen, display high efficiency and an inverse selectivity. The 2-aminopyridine group has been established as a highly effective recognition group in the binding of monosaccharides. The factors influencing the binding properties of receptors 1-15, which differ in the nature and number of binding and spacer subunits used as the buildings blocks, are discussed.