79791-45-0

Basic information

• Product Name: (S)-6-chloro-2,3-dihydro-<(1-phenylethyl)imino>-4H-1-benzopyran
• Synonyms: (S)-6-chloro-2,3-dihydro-<(1-phenylethyl)imino>-4H-1-benzopyran
• CAS NO: 79791-45-0
• Molecular Weight: 285.773
• Mol File: 79791-45-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-6-chloro-2,3-dihydro-<(1-phenylethyl)imino>-4H-1-benzopyran(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-6-chloro-2,3-dihydro-<(1-phenylethyl)imino>-4H-1-benzopyran(79791-45-0)
• EPA Substance Registry System: (S)-6-chloro-2,3-dihydro-<(1-phenylethyl)imino>-4H-1-benzopyran(79791-45-0)

Safety Data

• Hazardous Substances Data: 79791-45-0(Hazardous Substances Data)

Upstream product

• 37674-72-9 6-chloro-chroman-4-one 
• 2627-86-3 (S)-1-phenyl-ethylamine 

Downstream Products

• 79791-49-4 (S)-6-chloro-2,3-dihydro-3'-<(S)-1-phenylethyl>spiro<4H-1-benzopyran-4,4'-imidazolidine>-2',5'-dione 
• 79791-47-2 (S)-6-chloro-4-cyano-2,3-dihydro-4-<(S)-(1-phenylethyl)amino>-4H-1-benzopyran 

Relevant articles and documents

Synthesis of Optically Active Spirohydantoins by Asymmetric Induction. Hydantoin Formation from Amino Nitriles and Chlorosulfonyl Isocyanate

Conversion of 6-chloro- or 6-fluoro-2,3-dihydro-4H-1-benzopyran-4-one with optically active (S)-α-methylbenzylamine in the presence of TiCl4 to the ketimine followed by treatment in EtOH with HCN gas gives excellent yields of crystalline, enantiomerically pure (4S)-4-cyano-2,3-dihydro-6-chloro(or 6-fluoro)-4--4H-1-benzopyran.These sterically hindered amino nitriles react smoothly with chlorosulfonyl isocyanate to give, after hydrolysis, the hydantoins (4S)-2,3-dihydro-6-chloro(or 6-fluoro)-3'-spiro-2',5'-dione.The α-methylbenzyl groups can be removed by aqueous HBr/acetic acid to give the unprotected spirohydantoins.