8000-34-8

Basic information

• Product Name: Clove oil
• Synonyms: Oils,clove;Clove bud oil;Clove leaf oil;Clove stemoil;Clove stem oil;Essential clove oil;Essential oils, clove leaf;Eugenia caryophyllata bud oil;Eugenia caryophyllata leafoil;Oil of Clove;Oils, Eugenia caryophyllatabud;Oils,Syzygium aromaticum bud;Oils, Syzygiumaromaticum stem;Oils, clove bud;Oils, clove inflorescence;Oils, clove leaf;Oils, clove stem;Oils, essential, clove stem;Syzygiumaromaticum leaf oil;Syzygium aromaticum oil
• CAS NO: 8000-34-8
• Molecular Formula: Unspecified
• Molecular Weight: 205.64208
• EINECS: 215-185-5
• Product Categories: Essential oil
• Mol File: 8000-34-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 250 °C
• Flash Point: >230 °F
• Appearance: /
• Density: 1.05 g/mL at 25 °C
• Refractive Index: 1.521
• Water Solubility: Insoluble in water
• Stability: Stable. Probably combustible.
• Merck: 13,2443
• CAS DataBase Reference: Clove oil(CAS DataBase Reference)
• NIST Chemistry Reference: Clove oil(8000-34-8)
• EPA Substance Registry System: Clove oil(8000-34-8)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: R36/38:Irritating to eyes and skin.
• Safety Statements: 26-36
• WGK Germany: 3
• RTECS: GF6900000
• Hazardous Substances Data: 8000-34-8(Hazardous Substances Data)

Usage

Description

Clove oil, extracted from the clove plant Syzygium aromaticum, is an essential oil with various applications and health benefits. It is divided into three categories: bud oil, leaf oil, and stem oil. Clove oil is known for its strong anti-inflammatory properties, liver protection, and antimicrobial effects, making it a versatile natural remedy.

Uses

Used in Dental Care:
Clove oil is used as a local anesthetic for toothaches, providing relief from pain and inflammation. It is also used as an antiseptic for oral infections due to its broad-spectrum antimicrobial properties.
Used in Medicine:
Clove oil is used as an anti-inflammatory agent to protect the liver against disease and support overall liver health.
Used in Veterinary Care:
Clove oil is used as a uterine strengthener and aid in childbirth for animals, such as dogs and cats, in the week before giving birth. It is also used as an effective vermifuge or worm killer.
Used in Agriculture:
Clove oil is used as an effective insect repellent, making it suitable for use in herbal flea collars or added to herbal sprays.
Used in Digestive Health:
When taken internally, clove oil helps prevent flatulence, digestive problems, and diarrhea.
Used in Flavoring Agents:
Clove oil is used as a flavoring agent in various food products, such as tooth powder, confectionery, and some perfumery uses like honeysuckle, rose, balsam, aftershave fragrances, and herbal products.
Used in Odor Masking:
Clove bud oil, a type of clove oil, is used for its odor-masking properties, making it suitable for use in various applications where masking unpleasant odors is necessary.
Used in Microscopy:
Clove oil is used in microscopy as a medium for certain applications.

References

https://draxe.com/clove-oil-uses-benefits/ https://en.wikipedia.org/wiki/Oil_of_clove

Preparation

By water distillation of the buds of E. caryophyllata Thunb. (Fenarolfs Handbook of Flavor Ingredients, 1971).

Essential oil composition

Clove bud oil contains 70 to 90% eugenol, 2 to 17% eugenyl acetate, 5 to 12% α- and β-caryophyllene and traces of caryophyllene epoxide, gallic acid, flavonoids, oleanolic acid, rhamnetin, methyl salicylate, methyl-n-amyl ketone, methyln- heptyl ketone, methyl-n-amyl carbinol, methyl-n-heptyl carbinol, methyl alchohol, methyl benzoate, furfural, α-methyl furfural, furfuryl alchohol, vanillin and possibly β-pinene, valeraldehyde, methyl furfuryl alcohol and dimethyl furfural.*

Toxicity evaluation

The acute oral LD50 value in rats was reported as 2*65 g/kg (2.18-3.12 g/kg) (Moreno, 1973). The acute dermal LD50 value in rabbits was reported as approximately 5 g/kg (Moreno, 1973). The acute oral LD50 of clove oil for rats was found to be 372 mg/100-g rat (von Skramlik, 1959). Clove oil was toxic to mice when applied to the skin in two doses 7 days apart (Roe & Field, 1965).